Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019‏ - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Human viral oncogenesis: a cancer hallmarks analysis

EA Mesri, MA Feitelson, K Munger - Cell host & microbe, 2014‏ - cell.com
Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024‏ - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

[HTML][HTML] Viruses associated with human cancer

ME McLaughlin-Drubin, K Munger - … Acta (BBA)-Molecular Basis of Disease, 2008‏ - Elsevier
It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

DP Dittmer, B Damania - The Journal of clinical investigation, 2016‏ - jci.org
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Immortality of cell lines: challenges and advantages of establishment

M Irfan Maqsood, MM Matin, AR Bahrami… - Cell biology …, 2013‏ - Wiley Online Library
Cellular immortality happens upon impairment of cell‐cycle checkpoint pathways
(p53/p16/pRb), reactivation or up‐regulation of telomerase enzyme, or upregulation of some …

Human viruses and cancer

A Morales-Sánchez, EM Fuentes-Pananá - Viruses, 2014‏ - mdpi.com
The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010‏ - jci.org
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Modulation of B-cell exosome proteins by gamma herpesvirus infection

DG Meckes Jr, HP Gunawardena, RM Dekroon… - Proceedings of the …, 2013‏ - pnas.org
The human gamma herpesviruses, Kaposi sarcoma-associated virus (KSHV) and EBV, are
associated with multiple cancers. Recent evidence suggests that EBV and possibly other …

The role of gammaherpesviruses in cancer pathogenesis

HC Jha, S Banerjee, ES Robertson - Pathogens, 2016‏ - mdpi.com
Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …