Towards greener volatilomics: Is GC-IMS the new Swiss army knife of gas phase analysis?

H Parastar, P Weller - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
While GC-MS is still the standard in gas phase analysis or volatilomics, it is becoming
increasingly more cost-and resource-intensive with its high demand to infrastructure and …

Application of ion mobility spectrometry and the derived collision cross section in the analysis of environmental organic micropollutants

XC Song, E Canellas, N Dreolin… - Environmental …, 2023 - ACS Publications
Ion mobility spectrometry (IMS) is a rapid gas-phase separation technique, which can
distinguish ions on the basis of their size, shape, and charge. The IMS-derived collision …

Computational tools and algorithms for ion mobility spectrometry‐mass spectrometry

DH Ross, H Bhotika, X Zheng, RD Smith… - …, 2024 - Wiley Online Library
Ion mobility spectrometry‐mass spectrometry (IMS‐MS or IM‐MS) is a powerful analytical
technique that combines the gas‐phase separation capabilities of IM with the identification …

General method to obtain collision cross-section values in multipass high-resolution cyclic ion mobility separations

SC Habibi, G Nagy - Analytical chemistry, 2023 - ACS Publications
In recent years, ion mobility spectrometry-mass spectrometry (IMS-MS) has advanced the
field of omics-based research, especially with the development of high-resolution platforms; …

Electrochemical study of drug metabolism

N Nikzad, M Rafiee - Current Opinion in Electrochemistry, 2024 - Elsevier
Oxidation is the main pathway of drug metabolism and cytochrome P-450 (CYP450)
enzymes account for over 80% of drug oxidation. The chemical outcome of this first-pass …

Desorption electrospray ionization cyclic ion mobility-mass spectrometry imaging for traumatic brain injury spatial metabolomics

D Leontyev, H Olivos, B Shrestha… - Analytical …, 2024 - ACS Publications
Lipidomics focuses on investigating alterations in a wide variety of lipids that harness
important information on metabolic processes and disease pathology. However, the vast …

Automated 2D peak detection in gas chromatography-ion mobility spectrometry through persistent homology

H Parastar, J Christmann, P Weller - Analytica Chimica Acta, 2024 - Elsevier
Background Gas chromatography-ion mobility spectrometry (GC-IMS) is a powerful
analytical technique which has gained widespread use in a variety of fields. Detecting peaks …

Collision cross section measurement and prediction methods in omics

KY Kartowikromo, OE Olajide… - Journal of mass …, 2023 - Wiley Online Library
Omics studies such as metabolomics, lipidomics, and proteomics have become important for
understanding the mechanisms in living organisms. However, the compounds detected are …

Research progress on nanomaterial-based matrices for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis

X Du, L Yuan, S Gao, Y Tang, Z Wang, CQ Zhao… - … of Chromatography A, 2023 - Elsevier
Matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)
is a novel soft ionization bio-mass spectrometry technology emerging in the 1980s, which …

Monitoring kinetic processes of drugs and metabolites: Surface-enhanced Raman spectroscopy

Z Luo, H Chen, X Bi, J Ye - Advanced Drug Delivery Reviews, 2024 - Elsevier
Monitoring the kinetic changes of drugs and metabolites plays a crucial role in fundamental
research, preclinical and clinical application. Raman spectroscopy (RS) is regarded as a …