Integrative regulation of human brain blood flow
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …
humans. We revisit important concepts from the older literature and describe the interaction …
Selective neuronal loss in ischemic stroke and cerebrovascular disease
JC Baron, H Yamauchi, M Fujioka… - Journal of Cerebral …, 2014 - journals.sagepub.com
As a sequel of brain ischemia, selective neuronal loss (SNL)—as opposed to pannecrosis
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …
Age-associated reductions in cerebral blood flow are independent from regional atrophy
Prior studies have demonstrated decreasing cerebral blood flow (CBF) in normal aging, but
the full spatial pattern and potential mechanism of changes in CBF remain to be elucidated …
the full spatial pattern and potential mechanism of changes in CBF remain to be elucidated …
Hippocampal vascular reserve associated with cognitive performance and hippocampal volume
Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the
hippocampal region, yet little is known about the relationship between the richness of …
hippocampal region, yet little is known about the relationship between the richness of …
Regulation of the cerebral circulation by arterial carbon dioxide
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …
Cerebral blood flow changes during aging process and in cognitive disorders: A review
We aimed to summarize the available evidence on cerebral blood flow (CBF) changes in
normal aging and common cognitive disorders. We searched PubMed for studies on CBF …
normal aging and common cognitive disorders. We searched PubMed for studies on CBF …
A conceptual model for CO2-induced redistribution of cerebral blood flow with experimental confirmation using BOLD MRI
O Sobczyk, A Battisti-Charbonney, J Fierstra… - Neuroimage, 2014 - Elsevier
Cerebrovascular reactivity (CVR) is the change in cerebral blood flow (CBF) in response to a
change in a vasoactive stimulus. Paradoxical reductions in CBF in response to vasodilatory …
change in a vasoactive stimulus. Paradoxical reductions in CBF in response to vasodilatory …
Magnetic resonance imaging–based cerebrovascular reactivity and hemodynamic reserve: a review of method optimization and data interpretation
Given adequate perfusion pressure and nonlimiting intracranial or venous pressure,
cerebral blood flow (CBF) is regulated to match cerebral metabolic rate of oxygen (CMRO2) …
cerebral blood flow (CBF) is regulated to match cerebral metabolic rate of oxygen (CMRO2) …
Measuring cerebrovascular reactivity: the dynamic response to a step hypercapnic stimulus
J Poublanc, AP Crawley, O Sobczyk… - Journal of Cerebral …, 2015 - journals.sagepub.com
We define cerebral vascular reactivity (CVR) as the ratio of the change in blood oxygen level-
dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood …
dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood …
Neuroimaging assessment of cerebrovascular reactivity in concussion: current concepts, methodological considerations, and review of the literature
Concussion is a form of traumatic brain injury (TBI) that presents with a wide spectrum of
subjective symptoms and few objective clinical findings. Emerging research suggests that …
subjective symptoms and few objective clinical findings. Emerging research suggests that …