Forkhead box protein 3-expressing (FOXP3+) regulatory T cells (Treg cells) suppress
conventional T cells and are essential for immunological tolerance. FOXP3, the master …

Innate lymphoid cells (ILCs) are enriched at barrier surfaces of the mammalian body where
they rapidly respond to host, microbial or environmental stimuli to promote immunity or …

Neutrophils are implicated in multiple homeostatic and pathological processes, but whether
functional diversity requires discrete neutrophil subsets is not known. Here, we apply single …

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in the
paediatric population. JIA comprises a heterogeneous group of disorders with different onset …

Background Recent studies have suggested that the gut microbiota is altered in children
with juvenile idiopathic arthritis (JIA). However, age, sex, and body mass index (BMI) were …

Background Increasing evidence has proven that rheumatoid arthritis (RA) can aggravate
atherosclerosis (AS), and we aimed to explore potential diagnostic genes for patients with …

Juvenile idiopathic arthritis (JIA) is a chronic clinical condition characterized by arthritic
features in children under the age of 16, with at least 6 weeks of active symptoms. The …

Cytotoxic T lymphocytes (CTLs) are key effectors of the adaptive immune system that
recognize and eliminate virally infected and cancerous cells. In naive CD8+ T cells, T-cell …

Nuclear-factor, interleukin 3 regulated (NFIL3) is an immune regulator that plays an
essential role in autoimmune diseases. However, the relationship between rheumatoid …

Juvenile idiopathic arthritis (JIA) is highly heterogeneous in terms of etiology and clinical
presentation with ambiguity in JIA classification. The advance of high-throughput omics …