The biology of NKT cells
Recognized more than a decade ago, NKT cells differentiate from mainstream thymic
precursors through instructive signals emanating during TCR engagement by CD1d …
precursors through instructive signals emanating during TCR engagement by CD1d …
Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action
Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …
improved safety compared with traditional whole-pathogen vaccines. However, they are also …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
PJ Brennan, M Brigl, MB Brenner - Nature Reviews Immunology, 2013 - nature.com
Invariant natural killer T (iNKT) cells exist in a'poised effector'state, which enables them to
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …
rapidly produce cytokines following activation. Using a nearly monospecific T cell receptor …
Targeting natural killer cells and natural killer T cells in cancer
Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share
some phenotypical and functional similarities. Both cell types can rapidly respond to the …
some phenotypical and functional similarities. Both cell types can rapidly respond to the …
Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics
AH Merrill Jr - Chemical reviews, 2011 - ACS Publications
Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …
naming of sphingosine “in commemoration of the many enigmas which it presented to the …
An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo
Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but
emergence of viral variants that are antigenically distinct from the vaccine strains are of …
emergence of viral variants that are antigenically distinct from the vaccine strains are of …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
Recognition of CD1d-restricted antigens by natural killer T cells
Natural killer T (NKT) cells are innate-like T cells that rapidly produce a variety of cytokines
following T cell receptor (TCR) activation and can shape the immune response in many …
following T cell receptor (TCR) activation and can shape the immune response in many …
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
Y Kinjo, E Tupin, D Wu, M Fujio, R Garcia-Navarro… - Nature …, 2006 - nature.com
Natural killer T (NKT) cells recognize glycosphingolipids presented by CD1d molecules and
have been linked to defense against microbial infections. Previously defined foreign …
have been linked to defense against microbial infections. Previously defined foreign …