[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy
Y Wang, H Qi, Y Liu, C Duan, X Liu, T **a, D Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …
metabolism and are associated with a number of human diseases. The reprogramming of …
Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy
L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …
human health. An altered microbiome can be associated with complex diseases …
Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation
SY Lee, EK Jeong, MK Ju, HM Jeon, MY Kim, CH Kim… - Molecular cancer, 2017 - Springer
Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …
Transforming growth factor-β-induced cell plasticity in liver fibrosis and hepatocarcinogenesis
I Fabregat, D Caballero-Díaz - Frontiers in oncology, 2018 - frontiersin.org
The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …
different cellular processes that are essential for tissue and organ homeostasis. In the case …
Role of epithelial to mesenchymal transition in hepatocellular carcinoma
G Giannelli, P Koudelkova, F Dituri, W Mikulits - Journal of hepatology, 2016 - Elsevier
The epithelial to mesenchymal transition (EMT) is a multistep biological process whereby
epithelial cells change in plasticity by transient de-differentiation into a mesenchymal …
epithelial cells change in plasticity by transient de-differentiation into a mesenchymal …
A smart theranostic prodrug system activated by reactive oxygen species for regional chemotherapy of metastatic cancer
L Liu, F Liu, D Liu, W Yuan, M Zhang… - Angewandte …, 2022 - Wiley Online Library
Metastatic cancer is difficult to cure because of its uncontrollable nature and side effects
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …
Emerging strategies for treating metastasis
The systemic spread of tumor cells is the ultimate cause of the majority of deaths from
cancer, yet few successful therapeutic strategies have emerged to specifically target …
cancer, yet few successful therapeutic strategies have emerged to specifically target …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Oxidative stress in cancer therapy: friend or enemy?
M Azmanova, A Pitto‐Barry - Chembiochem, 2022 - Wiley Online Library
Excessive cellular oxidative stress is widely perceived as a key factor in pathophysiological
conditions and cancer development. Healthy cells use several mechanisms to maintain …
conditions and cancer development. Healthy cells use several mechanisms to maintain …