Tailor-made polysaccharides for biomedical applications
Polysaccharides (PSAs) are carbohydrate-based macromolecules widely used in the
biomedical field, either in their pure form or in blends/nanocomposites with other materials …
biomedical field, either in their pure form or in blends/nanocomposites with other materials …
Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review
Honeybees have been helpful insects since ancient centuries, and this benefit is not limited
to being a honey producer only. After the bee stings a person, pain, and swelling occur in …
to being a honey producer only. After the bee stings a person, pain, and swelling occur in …
Recent advances in the development and application of peptide self-assemblies in infection control
Peptide self-assemblies display distinct physical and structural transitions, featured from the
early small assemblies or oligomers, long nanosheets, nanobelts, nanotubes and …
early small assemblies or oligomers, long nanosheets, nanobelts, nanotubes and …
Interaction of designed cationic antimicrobial peptides with the outer membrane of gram-negative bacteria
S He, CM Deber - Scientific Reports, 2024 - nature.com
The outer membrane (OM) is a hallmark feature of gram-negative bacteria that provides the
species with heightened resistance against antibiotic threats while cationic antimicrobial …
species with heightened resistance against antibiotic threats while cationic antimicrobial …
Exploring the mechanism of photosensitizer conjugation on membrane perturbation of antimicrobial peptide: A multiscale molecular simulation study
Antimicrobial peptides (AMPs) exert their biological functions by perturbation with cellular
membrane. Conjugation of AMPs with photosensitizer (PS) is a promising strategy for …
membrane. Conjugation of AMPs with photosensitizer (PS) is a promising strategy for …
[HTML][HTML] Combination of a pH-responsive peptide amphiphile and a conventional antibiotic in treating Gram-negative bacteria
Background Clinical treatments of gastric infections using antibiotics suffer from the
undesired killing of commensal bacteria and emergence of antibiotic resistance. It is …
undesired killing of commensal bacteria and emergence of antibiotic resistance. It is …
Engineering the interaction of short antimicrobial peptides with bacterial barriers
While the rise of superbugs and new resistance mechanisms continues decreasing the
effectiveness of classical antibiotics, antimicrobial peptides (AMPs) are emerging as a new …
effectiveness of classical antibiotics, antimicrobial peptides (AMPs) are emerging as a new …
Advances in the clinical treatment of multidrug-resistant pathogens using polymyxins
Objectives Polymyxins are a vital class of antibiotics used to combat multidrug-resistant
Gram-negative bacteria. However, their use is limited due to potential nephrotoxicity and the …
Gram-negative bacteria. However, their use is limited due to potential nephrotoxicity and the …
Hylin-a1: A Pan-Inhibitor against Emerging and Re-Emerging Respiratory Viruses
Pandemic and epidemic outbreaks of respiratory viruses are a challenge for public health
and social care system worldwide, leading to high mortality and morbidity among the human …
and social care system worldwide, leading to high mortality and morbidity among the human …
[HTML][HTML] The limits of prediction: Why intrinsically disordered regions challenge our understanding of antimicrobial peptides
Antimicrobial peptides (AMPs) are molecules found in most organisms, playing a vital role in
innate immune defense against pathogens. Their mechanism of action involves the …
innate immune defense against pathogens. Their mechanism of action involves the …