[HTML][HTML] The emergence of multiscale connectomics-based approaches in stroke recovery

S Latifi, ST Carmichael - Trends in Neurosciences, 2024 - cell.com
Stroke is a leading cause of adult disability. Understanding stroke damage and recovery
requires deciphering changes in complex brain networks across different spatiotemporal …

Modulation of neural co-firing to enhance network transmission and improve motor function after stroke

K Ganguly, P Khanna, RJ Morecraft, DJ Lin - Neuron, 2022 - cell.com
Stroke is a leading cause of disability. While neurotechnology has shown promise for
improving upper limb recovery after stroke, efficacy in clinical trials has been variable. Our …

Cortical–hippocampal coupling during manifold exploration in motor cortex

J Kim, A Joshi, L Frank, K Ganguly - Nature, 2023 - nature.com
Abstract Systems consolidation—a process for long-term memory stabilization—has been
hypothesized to occur in two stages,,–. Whereas new memories require the hippocampus …

Activity-dependent transcriptional programs in memory regulate motor recovery after stroke

MT Joy, ST Carmichael - Communications Biology, 2024 - nature.com
Stroke causes death of brain tissue leading to long-term deficits. Behavioral evidence from
neurorehabilitative therapies suggest learning-induced neuroplasticity can lead to beneficial …

Rethinking remap**: Circuit mechanisms of recovery after stroke

B Campos, H Choi, AT DeMarco… - Journal of …, 2023 - jneurosci.org
Stroke is one of the most common causes of disability, and there are few treatments that can
improve recovery after stroke. Therapeutic development has been hindered because of a …

Transition from predictable to variable motor cortex and striatal ensemble patterning during behavioral exploration

S Kondapavulur, SM Lemke, D Darevsky, L Guo… - Nature …, 2022 - nature.com
Animals can capitalize on invariance in the environment by learning and automating highly
consistent actions; however, they must also remain flexible and adapt to environmental …

Motor cortex is responsible for motoric dynamics in striatum and the execution of both skilled and unskilled actions

MA Nicholas, EA Yttri - Neuron, 2024 - cell.com
Striatum and its predominant input, motor cortex, are responsible for the selection and
performance of purposive movement, but how their interaction guides these processes is not …

The role of dorsolateral striatum in the effects of deep cerebellar stimulation-mediated motor recovery following ischemic stroke in rodents

HH Chan, ND Mathews, H Khanna, N Mandava… - Experimental …, 2024 - Elsevier
Despite great advances in acute care and rehabilitation, stroke remains the leading cause of
motor impairment in the industrialized world. We have developed a deep brain stimulation …

Recovery of consolidation after sleep following stroke—interaction of slow waves, spindles, and GABA

J Kim, L Guo, A Hishinuma, S Lemke, DS Ramanathan… - Cell reports, 2022 - cell.com
Sleep is known to promote recovery after stroke. Yet it remains unclear how stroke affects
neural processing during sleep. Using an experimental stroke model in rats along with …

A versatile toolbox for studying cortical physiology in primates

K Khateeb, J Bloch, J Zhou, M Rahimi, DJ Griggs… - Cell Reports …, 2022 - cell.com
Lesioning and neurophysiological studies have facilitated the elucidation of cortical
functions and mechanisms of functional recovery following injury. Clinical translation of such …