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Circulating tumour DNA—looking beyond the blood
Over the past decade, various liquid biopsy techniques have emerged as viable alternatives
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …
Using circulating tumor DNA in colorectal cancer: current and evolving practices
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation
K Wang, X Wang, Q Pan, B Zhao - Molecular cancer, 2023 - Springer
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …
potential curative approach for PC, but most patients are unsuitable for operations when at …
Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …
[HTML][HTML] Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer
Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …
Application of cell-free DNA analysis to cancer treatment
RB Corcoran, BA Chabner - New England Journal of Medicine, 2018 - Mass Medical Soc
Emerging Roles of Cell-free Tumor DNA in Oncology The capacity to detect new cancers,
treatment-resistant variants, and tumor heterogeneity by noninvasive technology on the …
treatment-resistant variants, and tumor heterogeneity by noninvasive technology on the …
Detection and localization of surgically resectable cancers with a multi-analyte blood test
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins …
detect eight common cancer types through assessment of the levels of circulating proteins …
ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly develo** area …
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly develo** area …
The molecular landscape of head and neck cancer
CR Leemans, PJF Snijders, RH Brakenhoff - Nature Reviews Cancer, 2018 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …
Integrating liquid biopsies into the management of cancer
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …
compete with one another, with selective pressures leading to the emergence of …