While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

Repetitive transcranial magnetic stimulation (rTMS) is a widely used non-invasive
neuromodulatory technique. When applied in sleep medicine, the main hypothesis …

Deep brain regions such as hippocampus, insula, and amygdala are involved in
neuropsychiatric disorders, including chronic insomnia and depression. Our recent reports …

Insomnia (ID) is the most common sleep disorder; however pathogenetic mechanisms
underlying ID symptoms are not fully understood. Adopting a multifactorial view and …

Post-traumatic stress disorder (PTSD) is accompanied by disturbed sleep and an impaired
ability to learn and remember extinction of conditioned fear. Following a traumatic event, the …

Meta-analyses and systematic reviews have reported surprisingly few consistent insomnia-
characteristics with respect to cognitions, mood, traits, history of life events and family …

Sleep disturbances (eg, difficulty to initiate or maintain sleep) and poor sleep quality are
major health concerns that accompany several neurological and neuropsychiatric clinical …

Functional neuroimaging techniques have accelerated progress in the study of sleep
disorders. Considering the striking prevalence of these disorders in the general population …

Abstract Study Objectives: To examine neural correlates of working memory performance in
patients with primary insomnia (PIs) compared with well-matched good sleepers (GSs) …

Traumatic events have been increasingly recognized as important precipitants of clinically
significant insomnia. Trauma is an extreme form of stressful life event that generates a …