Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Intracellular delivery of advanced therapeutics, including biologicals and supramolecular
agents, is complex because of the natural biological barriers that have evolved to protect the …

The plasma membrane (PM) is often described as a wall, a physical barrier separating the
cell cytoplasm from the extracellular matrix (ECM). Yet, this wall is a highly dynamic structure …

Background Nanoinjection—the process of intracellular delivery using vertically configured
nanostructures—is a physical route that efficiently negotiates the plasma membrane, with …

Cell-based immunotherapy such as chimeric antigen receptor (CAR)-T therapy holds great
promise in treating cancer and other diseases; but the current viral-based method …

Surface topography on the scale of tens of nanometers to several micrometers substantially
affects cell adhesion, migration, and differentiation. Recent studies using electron …

Engineered nano–bio interfaces–driven by vertical micro/nanoneedles, nanoparticles, organ‐
on‐chip devices, and a diversity of nanosubstrates for mass spectroscopy imaging–are …

Tunable vertically aligned nanostructures, usually fabricated using inorganic materials, are
powerful nanoscale tools for advanced cellular manipulation. However, nanoscale precision …

The aquatic ecosystem is negatively impacted by organic dye contamination, which is now
one of the factors leading to environmental pollution. The present investigation involved the …

Nanofabrication technologies have been recently applied to the development of engineered
nano–bio interfaces for manipulating complex cellular processes. In particular, vertically …