Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and …

S Wiseman, F Marlborough, F Doubal… - Cerebrovascular …, 2014 - karger.com
Background: The cause of cerebral small vessel disease is not fully understood, yet it is
important, accounting for about 25% of all strokes. It also increases the risk of having …

Inflammation in ischemic stroke subtypes

A Tuttolomondo, D Di Raimondo… - Current …, 2012 - ingentaconnect.com
Determining the cause of stroke does influence choices for management. categorization of
subtypes of ischemic stroke has had considerable study, but definitions are hard to formulate …

Role of the platelets and nitric oxide biotransformation in ischemic stroke: a translative review from bench to bedside

M Bladowski, J Gawrys, D Gajecki… - Oxidative Medicine …, 2020 - Wiley Online Library
Ischemic stroke remains the fifth cause of death, as reported worldwide annually.
Endothelial dysfunction (ED) manifesting with lower nitric oxide (NO) bioavailability leads to …

Release of α-granule contents during platelet activation

CW Smith - Platelets, 2022 - Taylor & Francis
Upon activation, platelets release a plethora of factors which help to mediate their dynamic
functions in hemostasis, inflammation, wound healing, tumor metastasis and angiogenesis …

Endogenous extracellular vesicles participate in brain remodeling after ischemic stroke

MM Alvarez, FE Salazar, T Rodriguez… - International Journal of …, 2023 - mdpi.com
Brain remodeling after an ischemic stroke represents a promising avenue for exploring the
cellular mechanisms of endogenous brain repair. A deeper understanding of these …

Circulating markers of endothelial dysfunction and platelet activation in patients with severe symptomatic cerebral small vessel disease

PC Lavallée, J Labreuche, D Faille, MG Huisse… - Cerebrovascular …, 2013 - karger.com
Background: Small deep infarcts (SDI), also called lacunar infarcts, resulting from the
occlusion of deep branch arteries, account for 25% of ischemic strokes. The …

Increased thrombopoiesis and platelet activation in hantavirus-infected patients

AM Connolly-Andersen, E Sundberg… - The Journal of …, 2015 - academic.oup.com
Background. Thrombocytopenia is a common finding during viral hemorrhagic fever, which
includes hemorrhagic fever with renal syndrome (HFRS). The 2 main causes for …

Reconstruction of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal functional lncRNAs in Cerebral Infarction

JB Zou, HB Chai, XF Zhang, DY Guo, J Tai, Y Wang… - Scientific reports, 2019 - nature.com
Functioning as miRNA sponges, long non-coding RNA (lncRNA) exert its pharmacological
action via regulating expression of protein-coding genes. However, the lncRNA-mediated …

The PlA1/A2 polymorphism of glycoprotein IIIa as a risk factor for stroke: a systematic review and meta-analysis

CN Floyd, BH Ellis, A Ferro - PLoS One, 2014 - journals.plos.org
Background The PlA1/A2 polymorphism of glycoprotein IIIa (GPIIIa) has been reported to be
associated with risk of stroke in some studies, although other studies suggest no such …

Sepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study

N Layios, C Delierneux, A Hego, J Huart… - Intensive care medicine …, 2017 - Springer
Background Platelets have been involved in both immune surveillance and host defense
against severe infection. To date, whether platelet phenotype or other hemostasis …