Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019‏ - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

[HTML][HTML] Next-generation sequencing technologies and their application to the study and control of bacterial infections

J Besser, HA Carleton, P Gerner-Smidt… - Clinical microbiology …, 2018‏ - Elsevier
Background With the efficiency and the decreasing cost of next-generation sequencing, the
technology is being rapidly introduced into clinical and public health laboratory practice …

PlasmidFinder and in silico pMLST: identification and ty** of plasmid replicons in whole-genome sequencing (WGS)

A Carattoli, H Hasman - Horizontal gene transfer: methods and protocols, 2020‏ - Springer
PlasmidFinder and in silico plasmid multiLocus sequence ty** (pMLST) are two easy-to-
use web tools for detection and characterization of plasmid sequences in whole-genome …

Whole-genome sequencing of bacterial pathogens: the future of nosocomial outbreak analysis

S Quainoo, JPM Coolen, SAFT van Hijum… - Clinical microbiology …, 2017‏ - journals.asm.org
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

The current status on the taxonomy of Pseudomonas revisited: an update

A Peix, MH Ramírez-Bahena, E Velázquez - Infection, Genetics and …, 2018‏ - Elsevier
The genus Pseudomonas described in 1894 is one of the most diverse and ubiquitous
bacterial genera which encompass species isolated worldwide. In the last years more than …

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones

L Roer, S Overballe-Petersen, F Hansen, K Schønning… - MSphere, 2018‏ - journals.asm.org
Escherichia coli sequence type 410 (ST410) has been reported worldwide as an
extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation …

Molecular methods for detection of antimicrobial resistance

MF Anjum, E Zankari, H Hasman - Antimicrobial resistance in …, 2018‏ - Wiley Online Library
Molecular characterization of the genetic mechanism (s) underlying a given phenotypic
result, obtained by traditional antimicrobial sensitivity testing, is now an integral part of many …

Whole genome sequencing reveals hidden transmission of carbapenemase-producing Enterobacterales

K Marimuthu, I Venkatachalam, V Koh… - Nature …, 2022‏ - nature.com
Carbapenemase-producing Enterobacterales (CPE) infection control practices are based on
the paradigm that detected carriers in the hospital transmit to other patients who stay in the …

[HTML][HTML] Hospital effluent: A reservoir for carbapenemase-producing Enterobacterales?

N Cahill, L O'Connor, B Mahon, Á Varley… - Science of the Total …, 2019‏ - Elsevier
Antimicrobial resistance is a major public health concern. Carbapenemase-producing
Enterobacterales (CPE) represent a significant health threat as some strains are resistant to …

Whole-genome sequencing as part of national and international surveillance programmes for antimicrobial resistance: a roadmap

NIHR Global Health Research Unit on Genomic … - BMJ global …, 2020‏ - gh.bmj.com
The global spread of antimicrobial resistance (AMR) and lack of novel alternative treatments
have been declared a global public health emergency by WHO. The greatest impact of AMR …