Many proteins and peptides can form amyloid‐like structures both in vivo and in vitro.
Although strikingly similar fibrillar structures can be observed across a variety of amino acid …

In 2008, I reviewed and proposed a model for our discovery in 2005 that unrefoldable and
insoluble proteins could in fact be solubilized in unsalted water. Since then, this discovery …

Neuropeptides and peptide hormones are stored in the amyloid state in dense-core vesicles
of secretory cells. Secreted peptides experience dramatic environmental changes in the …

Alzheimer's disease (AD) onset is associated with changes in hypothalamic-pituitary–
gonadal (HPG) function. The 54 amino acid kisspeptin (KP) peptide regulates the HPG axis …

The 219-residue protein p25α stimulates the fibrillation of α-synuclein (αSN) in vitro and
colocalizes with it in several α-synucleinopathies. Although p25α does not fibrillate by itself …

Amyloids are highly ordered cross‐β‐sheet containing protein aggregates associated with
several dozens diseases including Alzheimer's, Creutzfeldt‐Jakob and Parkinson's disease …

Kisspeptins are peptide products of Kiss-1 gene and have been substantially associated
with the initiation of puberty by virtue of their ability to cause pulsatile release of GnRH …

Amyloids are insoluble fibrous protein aggregates that share in common the socalled cross-
β sheet structure. Protein depositions found initially in patients with neurological disorders …

In 2008, I reviewed and proposed a model for our discovery in 2005 that unrefoldable and
insoluble proteins could in fact be solubilized in unsalted water. Since then, this discovery …

Islet transplantation has great promise as a treatment for patients with insulin-dependent
diabetes but its long-term success is limited by progressive graft dysfunction. Many …