Three waves changes, new variant strains, and vaccination effect against COVID-19 pandemic
It has been more than one year since the first case of the coronaviruses was infected by
COVID-19 in China. The world witnessed three waves of the corona virus till now, and more …
COVID-19 in China. The world witnessed three waves of the corona virus till now, and more …
[HTML][HTML] Will mutations in the spike protein of SARS-CoV-2 lead to the failure of COVID-19 vaccines?
Z Jia, W Gong - Journal of Korean medical science, 2021 - synapse.koreamed.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19), which has spread worldwide since it was first …
coronavirus disease 2019 (COVID-19), which has spread worldwide since it was first …
Immunogenicity and efficacy of vaccine boosters against SARS-CoV-2 Omicron subvariant BA. 5 in male Syrian hamsters
RRG Machado, JL Walker, D Scharton… - Nature …, 2023 - nature.com
Abstract The SARS-CoV-2 Omicron subvariant BA. 5 rapidly spread worldwide and replaced
BA. 1/BA. 2 in many countries, becoming globally dominant. BA. 5 has unique amino acid …
BA. 1/BA. 2 in many countries, becoming globally dominant. BA. 5 has unique amino acid …
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization
A Ebenig, S Muraleedharan, J Kazmierski, D Todt… - Cell reports, 2022 - cell.com
Vaccine-associated enhanced respiratory disease (VAERD) is a severe complication for
some respiratory infections. To investigate the potential for VAERD induction in coronavirus …
some respiratory infections. To investigate the potential for VAERD induction in coronavirus …
ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants
Abstract ChAdOx1 nCoV-19 (AZD1222) is a replication-deficient simian adenovirus–
vectored vaccine encoding the spike (S) protein of SARS-CoV-2, based on the first …
vectored vaccine encoding the spike (S) protein of SARS-CoV-2, based on the first …
Updated vaccine protects against SARS-CoV-2 variants including Omicron (B. 1.1. 529) and prevents transmission in hamsters
S Sharma, T Vercruysse, L Sanchez-Felipe… - Nature …, 2022 - nature.com
Current COVID-19 vaccines are based on prototypic spike sequences from ancestral 2019
SARS-CoV-2 strains. However, the ongoing pandemic is fueled by variants of concern …
SARS-CoV-2 strains. However, the ongoing pandemic is fueled by variants of concern …
Protective efficacy of Ad26. COV2. S against SARS-CoV-2 B. 1.351 in macaques
The emergence of SARS-CoV-2 variants that partially evade neutralizing antibodies poses a
threat to the efficacy of current COVID-19 vaccines,. The Ad26. COV2. S vaccine expresses …
threat to the efficacy of current COVID-19 vaccines,. The Ad26. COV2. S vaccine expresses …
Immunity elicited by natural infection or Ad26. COV2. S vaccination protects hamsters against SARS-CoV-2 variants of concern
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern have
emerged and may pose a threat to both the efficacy of vaccines based on the original …
emerged and may pose a threat to both the efficacy of vaccines based on the original …
Full efficacy and long-term immunogenicity induced by the SARS-CoV-2 vaccine candidate MVA-CoV2-S in mice
A Lázaro-Frías, P Pérez, C Zamora… - Npj Vaccines, 2022 - nature.com
Two doses of the MVA-CoV2-S vaccine candidate expressing the SARS-CoV-2 spike (S)
protein protected K18-hACE2 transgenic mice from a lethal dose of SARS-CoV-2. This …
protein protected K18-hACE2 transgenic mice from a lethal dose of SARS-CoV-2. This …
SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern
DW Hawman, K Meade-White, J Archer, SS Leventhal… - Elife, 2022 - elifesciences.org
Despite mass public health efforts, the SARS-CoV2 pandemic continues as of late 2021 with
resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants …
resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants …