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Circuit mechanisms of Parkinson's disease
MM McGregor, AB Nelson - Neuron, 2019 - cell.com
Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …
second most common neurodegenerative disorder after Alzheimer's disease, it affects …
Parkinson's disease dementia: a neural networks perspective
J Gratwicke, M Jahanshahi, T Foltynie - Brain, 2015 - academic.oup.com
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …
90% of patients with Parkinson's disease. With increasing life expectancy in western …
Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating
Cravings that precede loss of control (LOC) over food consumption present an opportunity
for intervention in patients with the binge eating disorder (BED). In this pilot study, we used …
for intervention in patients with the binge eating disorder (BED). In this pilot study, we used …
Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation
A current issue in the research of augmentation of brain functions using transcranial
electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar …
electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar …
[HTML][HTML] Dynamic network communication as a unifying neural basis for cognition, development, aging, and disease
Perception, cognition, and social interaction depend upon coordinated neural activity. This
coordination operates within noisy, overlap**, and distributed neural networks operating …
coordination operates within noisy, overlap**, and distributed neural networks operating …
Tuning pathological brain oscillations with neurofeedback: a systems neuroscience framework
Neurofeedback (NFB) is emerging as a promising technique that enables self-regulation of
ongoing brain oscillations. However, despite a rise in empirical evidence attesting to its …
ongoing brain oscillations. However, despite a rise in empirical evidence attesting to its …
Neuromodulation for brain disorders: challenges and opportunities
The field of neuromodulation encompasses a wide spectrum of interventional technologies
that modify pathological activity within the nervous system to achieve a therapeutic effect …
that modify pathological activity within the nervous system to achieve a therapeutic effect …
Bilateral deep brain stimulation of the nucleus basalis of Meynert for Parkinson disease dementia: a randomized clinical trial
Importance Deep brain stimulation of the nucleus basalis of Meynert (NBM DBS) has been
proposed as a treatment option for Parkinson disease dementia. Objective To evaluate the …
proposed as a treatment option for Parkinson disease dementia. Objective To evaluate the …
Frequency-specific optogenetic deep brain stimulation of subthalamic nucleus improves parkinsonian motor behaviors
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating …
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating …
[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?
T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …