Bone defects caused by trauma, tumor, congenital abnormality and osteoarthritis, etc. have
been substantially impacted the lives and health of human. Artificial bone implants, like …

Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

Chronic osteomyelitis is a challenging disease due to its serious rates of mortality and
morbidity while the currently available treatment strategies are suboptimal. In contrast to the …

Intractable bacterial infections and insufficient osseointegration are two major concerns
plaguing the repair of infected bone defects. Many attempts use antibiotics coatings on the …

Osseous tissue repair has advanced due to the introduction of tissue engineering. The key
elements required while engineering new tissues involve scaffolds, cells, and bioactive …

The periosteum is an indispensable part of the bone that nourishes the cortical bone and
acts as a repertoire of osteoprogenitor cells. Periosteal damage as a result of traumatic …

Due to their poor light penetration, photothermal therapy and photodynamic therapy are
ineffective in treating deep tissue infections, such as osteomyelitis caused by …

Orthopedic diseases (eg, fracture, bone tumor, osteoarthritis, osteoporosis, chronic
inflammation, and infection) can result in locomotion disability, loss of protection for other …

This review presents principles and novelties in the field of tissue optical clearing (TOC)
technology, as well as application for optical monitoring of drug delivery and effective …

Promoting bone regeneration while inhibiting bacterial infection is still clinical challenge in
the repair of infectious bone defects. Herein, a vancomycin-loaded silica coating with …