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Humic acids: Structural properties and multiple functionalities for novel technological developments
Humic acids (HAs) are macromolecules that comprise humic substances (HS), which are
organic matter distributed in terrestrial soil, natural water, and sediment. HAs differ from the …
organic matter distributed in terrestrial soil, natural water, and sediment. HAs differ from the …
The current role of cannabis and cannabinoids in health: A comprehensive review of their therapeutic potential
There has been an increased interest of the scientific community in cannabis and its
constituents for therapeutic purposes. Although it is believed that cannabinoids can be …
constituents for therapeutic purposes. Although it is believed that cannabinoids can be …
[HTML][HTML] Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer
In spite of the huge advancements in both diagnosis and interventions, hormone refractory
prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic …
prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic …
Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities
Cannabis has long been used for healing and recreation in several regions of the world.
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been …
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been …
Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update
P Morales, L Hernandez-Folgado, P Goya… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Modulation of the CB2 receptor is an interesting approach for pain and
inflammation, arthritis, addictions, neuroprotection, and cancer, among other possible …
inflammation, arthritis, addictions, neuroprotection, and cancer, among other possible …
[HTML][HTML] Cannabinoids and PPAR ligands: the future in treatment of polycystic ovary syndrome women with obesity and reduced fertility
P Przybycień, D Gąsior-Perczak, W Placha - Cells, 2022 - mdpi.com
Cannabinoids (CBs) are used to treat chronic pain, chemotherapy-induced nausea and
vomiting, and multiple sclerosis spasticity. Recently, the medicinal use of CBs has attracted …
vomiting, and multiple sclerosis spasticity. Recently, the medicinal use of CBs has attracted …
Relevance of peroxisome proliferator activated receptors in multitarget paradigm associated with the endocannabinoid system
Cannabinoids have shown to exert their therapeutic actions through a variety of targets.
These include not only the canonical cannabinoid receptors CB1R and CB2R but also …
These include not only the canonical cannabinoid receptors CB1R and CB2R but also …
[HTML][HTML] The pathophysiology and the therapeutic potential of cannabinoids in prostate cancer
Simple Summary Prostate cancer, after lung cancer, is the leading cause of death among
men. The incidence rate of prostate cancer varies worldwide between regions and …
men. The incidence rate of prostate cancer varies worldwide between regions and …
Novel approaches and current challenges with targeting the endocannabinoid system
Introduction The pathophysiological relevance of the endocannabinoid system has been
widely demonstrated in a variety of diseases including cancer, neurological disorders, and …
widely demonstrated in a variety of diseases including cancer, neurological disorders, and …
Cannabinoid quinones—A review and novel observations
A cannabinoid anticancer para-quinone, HU-331, which was synthesized by our group five
decades ago, was shown to have very high efficacy against human cancer cell lines in-vitro …
decades ago, was shown to have very high efficacy against human cancer cell lines in-vitro …