The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …

Analyzing vertebrate genomes requires rapid mRNA/DNA and cross-species protein
alignments. A new tool, BLAT, is more accurate and 500 times faster than popular existing …

The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

The sequence of the human genome encodes the genetic instructions for human
physiology, as well as rich information about human evolution. In 2001, the International …

The SWISS-PROT protein knowledgebase (http://www. expasy. org/sprot/and http://www.
ebi. ac. uk/swissprot/) connects amino acid sequences with the current knowledge in the Life …

Proteomics, the large-scale analysis of proteins, will contribute greatly to our understanding
of gene function in the post-genomic era. Proteomics can be divided into three main …