Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer-related deaths worldwide. Although the prognosis of patients with HCC is …

Maintenance of plasma membrane integrity is essential for normal cell viability and function.
Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of …

The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …

An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is
currently critical for improving the prognosis and reducing the associated economic burden …

The majority of ovarian cancer patients present with advanced disease and despite
aggressive treatment, prognosis remains poor. Significant improvement in ovarian cancer …

Tumor-derived exosomes are emerging mediators of tumorigenesis and tissue-specific
metastasis. Proteomic profiling has identified Annexin II as one of the most highly expressed …

Distant organ metastasis, often termed as organotropic metastasis or metastatic
organotropism, is a fundamental feature of malignant tumours and accounts for most cancer …

Background Exosomes are small membranous vesicles secreted into body fluids by multiple
cell types, including tumor cells, and in various disease conditions. Tumor exosomes contain …