Olfactory dysfunction in neurodegenerative diseases

C Marin, D Vilas, C Langdon, I Alobid… - Current allergy and …, 2018 - Springer
Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

The concept of prodromal Parkinson's disease

P Mahlknecht, K Seppi… - Journal of Parkinson's …, 2015 - content.iospress.com
Parkinson's disease (PD) is currently clinically defined by a set of cardinal motor features
centred on the presence of bradykinesia and at least one additional motor symptom out of …

Olfactory bulb involvement in neurodegenerative diseases

J Attems, L Walker, KA Jellinger - Acta neuropathologica, 2014 - Springer
Olfactory dysfunction is a common and early symptom of many neurodegenerative diseases,
particularly of Parkinson's disease and other synucleinopathies, Alzheimer's disease (AD) …

Diffusion tensor imaging in parkinsonian syndromes: a systematic review and meta-analysis

CJ Cochrane, KP Ebmeier - Neurology, 2013 - AAN Enterprises
Objectives: We performed a systematic review to assess alterations in measures of diffusion
tensor imaging (DTI) in parkinsonian syndromes, exploring the potential role of DTI in …

The human olfactory system in two proteinopathies: Alzheimer's and Parkinson's diseases

I Ubeda-Bañon, D Saiz-Sanchez… - Translational …, 2020 - Springer
Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative disorders.
Their etiologies are idiopathic, and treatments are symptomatic and orientated towards …

White matter microstructure deteriorates across cognitive stages in Parkinson disease

TR Melzer, R Watts, MR MacAskill, TL Pitcher… - Neurology, 2013 - AAN Enterprises
Objectives: To characterize different stages of Parkinson disease (PD)-related cognitive
decline using diffusion tensor imaging (DTI) and investigate potential relationships between …

Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders

IC Mundinano, MC Caballero, C Ordóñez… - Acta …, 2011 - Springer
Olfactory dysfunction is a frequent and early feature of patients with neurodegenerative
disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD) and is very …

Diffusion tensor imaging in Parkinson's disease and parkinsonian syndrome: a systematic review

Y Zhang, MA Burock - Frontiers in neurology, 2020 - frontiersin.org
Diffusion tensor imaging (DTI) allows measuring fractional anisotropy and similar
microstructural indices of the brain white matter. Lower than normal fractional anisotropy as …

Principles of diffusion kurtosis imaging and its role in early diagnosis of neurodegenerative disorders

A Arab, A Wojna-Pelczar, A Khairnar, N Szabó… - Brain research …, 2018 - Elsevier
Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as
extracellular changes which lead to neuronal degeneration. The central nervous system …

Neural plasticity in human brain connectivity: the effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease

TJ Van Hartevelt, J Cabral, G Deco, A Møller… - PloS one, 2014 - journals.plos.org
Background Positive clinical outcomes are now well established for deep brain stimulation,
but little is known about the effects of long-term deep brain stimulation on brain structural …