Recent advances bioactive 1, 2, 4-triazole-3-thiones

ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

Nascent pharmacological advancement in adamantane derivatives

A Ragshaniya, V Kumar, RK Tittal… - Archiv der Pharmazie, 2024 - Wiley Online Library
The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …

Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1, 3, 4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1, 3, 4 …

AA Kadi, NR El-Brollosy, OA Al-Deeb, EE Habib… - European journal of …, 2007 - Elsevier
Reaction of 1-adamantanecarbonyl chloride with certain carboxylic acid hydrazides in
pyridine yielded the corresponding N-acyl adamantane-1-carbohydrazide derivatives 3a–j …

Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1, 3, 4-thiadiazole derivatives

AA Kadi, ES Al-Abdullah, IA Shehata, EE Habib… - European journal of …, 2010 - Elsevier
New 1-adamanyl-1, 3, 4-thiadiazole derivatives namely, 5-(1-adamantyl)-1, 3, 4-
thiadiazoline-2-thione 3, 5-(1-adamantyl)-3-(benzyl-or 4-substituted benzyl)-1, 3, 4 …

Synthesis of some novel heterocyclic compounds derived from diflunisal hydrazide as potential anti-infective and anti-inflammatory agents

ŞG Küçükgüzel, İ Küçükgüzel, E Tatar, S Rollas… - European Journal of …, 2007 - Elsevier
Three novel series of 2′, 4′-difluoro-4-hydroxybiphenyl-3-carboxylic acid derivatives
namely 4-substituted-1, 2, 4-triazoline-3-thiones (4a–g); 2-substituted-1, 3, 4-thiadiazoles …

Synthesis and antioxidant activity evaluation of new compounds from hydrazinecarbothioamide and 1, 2, 4-triazole class containing diarylsulfone and 2, 4 …

SF Barbuceanu, DC Ilies, G Saramet… - International Journal of …, 2014 - mdpi.com
In the present investigation, new hydrazinecarbothioamides 4–6 were synthesized by
reaction of 4-(4-X-phenylsulfonyl) benzoic acids hydrazides (X= H, Cl, Br) 1–3 with 2, 4 …

Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1, 2, 4-triazoline-3-thiones

AA El-Emam, AMS Al-Tamimi, MA Al-Omar… - European journal of …, 2013 - Elsevier
Abstract The reaction of 5-(1-adamantyl)-4-substituted-1, 2, 4-triazoline-3-thione 5a, b and
10a, b with formaldehyde solution and various primary aromatic amines or 1-substituted …

Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents

O Kouatly, A Geronikaki, C Kamoutsis… - European journal of …, 2009 - Elsevier
A series of adamantane derivatives of thiazolyl-N-substituted amides were synthesized in a
three-step reaction and tested for anti-inflammatory activity as well as lipoxygenase and …

Synthesis, antimicrobial, and anti-inflammatory activities of novel 5-(1-adamantyl)-4-arylideneamino-3-mercapto-1, 2, 4-triazoles and related derivatives

MA Al-Omar, ES Al-Abdullah, IA Shehata, EE Habib… - Molecules, 2010 - mdpi.com
The reaction of 5-(1-adamantyl)-4-amino-3-mercapto-1, 2, 4-triazole (5) with various
aromatic aldehydes in ethanol or acetic acid yielded the corresponding 4-arylideneamino …

Thiazolo [3, 2-b]-1, 2, 4-triazole-5 (6H)-one substituted with ibuprofen: Novel non-steroidal anti-inflammatory agents with favorable gastrointestinal tolerance

A Uzgören-Baran, BC Tel, D Sarıgöl, Eİ Öztürk… - European journal of …, 2012 - Elsevier
In an effort to establish new candidates with improved analgesic and anti-inflammatory
activities and lower ulcerogenic risk, a series of thiazolo [3, 2-b]-1, 2, 4-triazole-5 (6H)-one …