Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Non-viral vectors for RNA delivery

Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy

Y Zou, X Sun, Q Yang, M Zheng, O Shimoni… - Science …, 2022 - science.org
We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling,
noninvasive brain delivery and tumor cell targeting, demonstrating an effective and safe …

Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …

S Kansız, YM Elçin - Advances in Colloid and Interface Science, 2023 - Elsevier
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …

[HTML][HTML] Recent progress in drug delivery

C Li, J Wang, Y Wang, H Gao, G Wei, Y Huang… - … pharmaceutica sinica B, 2019 - Elsevier
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Carriers break barriers in drug delivery: endocytosis and endosomal escape of gene delivery vectors

IMS Degors, C Wang, ZU Rehman… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Over the past decades, major efforts were undertaken to develop devices on a
nanoscale level for the efficient and nontoxic delivery of molecules to tissues and cells, for …

Aliphatic polycarbonates from cyclic carbonate monomers and their application as biomaterials

W Yu, E Maynard, V Chiaradia, MC Arno… - Chemical …, 2021 - ACS Publications
Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

In vivo gene delivery mediated by non-viral vectors for cancer therapy

R Mohammadinejad, A Dehshahri… - Journal of Controlled …, 2020 - Elsevier
Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …