Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Bioorthogonal Guided Activation of cGAS‐STING by AIE Photosensitizer Nanoparticles for Targeted Tumor Therapy and Imaging

M Cui, D Tang, B Wang, H Zhang, G Liang… - Advanced …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) and photothermal therapy (PTT) leverage reactive oxygen
species (ROS) and control local hyperthermia by photosensitizer to perturb intracellular …

Synthesizing biomaterials in living organisms

X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …

Assembly drives regioselective azide-alkyne cycloaddition reaction

Q Jiang, W Zhan, X Liu, L Bai, M Wang, Y Xu… - Nature …, 2023 - nature.com
Azide-alkyne cycloaddition reaction is a very common organic reaction to synthesize
nitrogen-containing heterocycles. Once catalyzed by Cu (I) or Ru (II), it turns out to be a click …

Polymerization in living organisms

D Wu, J Lei, Z Zhang, F Huang, M Buljan… - Chemical Society …, 2023 - pubs.rsc.org
Vital biomacromolecules, such as RNA, DNA, polysaccharides and proteins, are
synthesized inside cells via the polymerization of small biomolecules to support and multiply …

[HTML][HTML] In situ formed scaffold with royal jelly-derived extracellular vesicles for wound healing

D Tan, W Zhu, L Liu, Y Pan, Y Xu, Q Huang, L Li… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Safe and effective wound healing can be a major clinical challenge.
Inflammation and vascular impairment are two main causes of inadequate wound healing …

Clickable polysaccharides for biomedical applications: a comprehensive review

MK Yazdi, SM Sajadi, F Seidi, N Rabiee… - Progress in polymer …, 2022 - Elsevier
Recent advances in materials science and engineering highlight the importance of
designing sophisticated biomaterials with well-defined architectures and tunable properties …

[HTML][HTML] Advances and prospects of RAFT polymerization-derived nanomaterials in MRI-assisted biomedical applications

W Zhao, C Li, J Chang, H Zhou, D Wang, J Sun… - Progress in Polymer …, 2023 - Elsevier
Magnetic resonance imaging (MRI) is recognized as the most powerful clinical imaging
modality due to its ability to produce detailed three-dimensional anatomical images and high …

Curbing exosome communications via introducing artificial membrane receptors for metastatic pancreatic cancer therapy

M Deng, R Guo, Y Wang, JX Li, J He, M Li… - Advanced …, 2023 - Wiley Online Library
Tumor‐derived exosomes (TDEs) carry various biomolecular cargos and play crucial roles
in metastasis. TDEs migrate to distal organs for intercellular communication and induce the …