Threats posed by the fungal kingdom to humans, wildlife, and agriculture

MC Fisher, SJ Gurr, CA Cuomo, DS Blehert, H **… - MBio, 2020 - journals.asm.org
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …

Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Malassezia: A Commensal, Pathogen, and Mutualist of Human and Animal Skin

G Ianiri, S LeibundGut-Landmann… - Annual Review of …, 2022 - annualreviews.org
Identified in the late nineteenth century as a single species residing on human skin,
Malassezia is now recognized as a diverse genus comprising 18 species inhabiting not only …

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …

G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - journals.asm.org
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Efflux-mediated antifungal drug resistance

RD Cannon, E Lam**, AR Holmes… - Clinical microbiology …, 2009 - journals.asm.org
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature Reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

Cryptococcal cell morphology affects host cell interactions and pathogenicity

LH Okagaki, AK Strain, JN Nielsen, C Charlier… - PLoS …, 2010 - journals.plos.org
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …

[HTML][HTML] Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans

OW Liu, CD Chun, ED Chow, C Chen, HD Madhani… - Cell, 2008 - cell.com
The fungus Cryptococcus neoformans is a leading cause of mortality and morbidity among
HIV-infected individuals. We utilized the completed genome sequence and optimized …

The Biology of the Cryptococcus neoformans Species Complex

X Lin, J Heitman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …