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Threats posed by the fungal kingdom to humans, wildlife, and agriculture
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …
respect to its profound impact on global health, biodiversity, ecology, agriculture …
Cryptococcus: from environmental saprophyte to global pathogen
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
Malassezia: A Commensal, Pathogen, and Mutualist of Human and Animal Skin
Identified in the late nineteenth century as a single species residing on human skin,
Malassezia is now recognized as a diverse genus comprising 18 species inhabiting not only …
Malassezia is now recognized as a diverse genus comprising 18 species inhabiting not only …
Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Efflux-mediated antifungal drug resistance
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …
Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …
because of its tendency to infect immunocompromised individuals, particularly those …
Cryptococcal cell morphology affects host cell interactions and pathogenicity
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …
[HTML][HTML] Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
The fungus Cryptococcus neoformans is a leading cause of mortality and morbidity among
HIV-infected individuals. We utilized the completed genome sequence and optimized …
HIV-infected individuals. We utilized the completed genome sequence and optimized …
The Biology of the Cryptococcus neoformans Species Complex
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …
immunocompromised patients. Despite recent advances in the genetics and molecular …