In recent decades, mass spectrometry has moved more than ever before into the front line of
protein-centered research. After being established at the qualitative level, the more …

Mass spectrometry-based proteomics empowers deep profiling of proteome and protein
posttranslational modifications (PTMs) in Alzheimer's disease (AD). Here we review the …

Over the last few decades, mass spectrometry‐based proteomics has become an
increasingly powerful tool that is now able to routinely detect and quantify thousands of …

In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …

Mass spectrometry (MS) has emerged at the forefront of quantitative proteomic techniques.
Liquid chromatography‐mass spectrometry (LC‐MS) can be used to determine abundances …

Metabolomics and exposomics are important in the studies of human health and diseases.
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …

Mass spectrometry–based quantitative proteomics is a powerful tool for gaining insights into
function and dynamics of biological systems. However, peptides with different sequences …

Multiplexed isobaric labeling methods, such as tandem mass tags (TMT), remarkably
improve the throughput of quantitative mass spectrometry. Here, we present a 27-plex TMT …

As the body fluid that directly interchanges with the extracellular fluid of the central nervous
system (CNS), cerebrospinal fluid (CSF) serves as a rich source for CNS-related disease …

Recent developments in mass spectrometry-based single-cell proteomics (SCP) have
resulted in dramatically improved sensitivity, yet the relatively low measurement throughput …