Global Cancer Statistics 2022: the trends projection analysis
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …
year. The disease variations in different parts of the world, the impact of available medical …
Hyaluronic acid for anticancer drug and nucleic acid delivery
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
Doxorubicin-based hybrid compounds as potential anticancer agents: a review
The scarcity of novel and effective therapeutics for the treatment of cancer is a pressing and
alarming issue that needs to be prioritized. The number of cancer cases and deaths are …
alarming issue that needs to be prioritized. The number of cancer cases and deaths are …
[HTML][HTML] Anticancer activities of fatty acids and their heterocyclic derivatives
M Jóźwiak, A Filipowska, F Fiorino, M Struga - European journal of …, 2020 - Elsevier
Traditional chemotherapy relies on the premise that rapidly proliferating cancer cells are
more likely to be killed by a cytotoxic agent, but in reality, the long-standing problem of …
more likely to be killed by a cytotoxic agent, but in reality, the long-standing problem of …
Anti-biofilm properties of bacterial di-rhamnolipids and their semi-synthetic amide derivatives
A new strain, namely Lysinibacillus sp. BV152. 1 was isolated from the rhizosphere of
ground ivy (Glechoma hederacea L.) producing metabolites with potent ability to inhibit …
ground ivy (Glechoma hederacea L.) producing metabolites with potent ability to inhibit …
Design and biological evaluation of cell-penetrating peptide–doxorubicin conjugates as prodrugs
Doxorubicin (Dox) is a hydrophilic anticancer drug that has short retention time due to the
efficient efflux in some cancer cells (eg, ovarian adenocarcinoma SK-OV-3). Cyclic [W (RW) …
efficient efflux in some cancer cells (eg, ovarian adenocarcinoma SK-OV-3). Cyclic [W (RW) …
Molecular Switches—Tools for Imparting Control in Drug Delivery Systems
Cancer is a globally prevalent cause of premature mortality. Of growing interest is the
development of novel anticancer therapies and the optimisation of associated risks. Major …
development of novel anticancer therapies and the optimisation of associated risks. Major …
Design and application of hybrid cyclic-linear peptide-doxorubicin conjugates as a strategy to overcome doxorubicin resistance and toxicity
Doxorubicin (Dox) is used for breast cancer, leukemia, and lymphoma treatment as an
effective chemotherapeutic agent. However, Dox use is restricted due to inherent and …
effective chemotherapeutic agent. However, Dox use is restricted due to inherent and …
Self-Assembling Doxorubicin–Tocopherol Succinate Prodrug as a New Drug Delivery System: Synthesis, Characterization, and in Vitro and in Vivo Anticancer …
N Duhem, F Danhier, V Pourcelle… - Bioconjugate …, 2014 - ACS Publications
Self-assembled prodrugs forming nanoaggregates are a promising approach to enhance
the antitumor efficacy and to reduce the toxicity of anticancer drugs. To achieve this goal …
the antitumor efficacy and to reduce the toxicity of anticancer drugs. To achieve this goal …
Synthesis, anticancer activities, and cellular uptake studies of lipophilic derivatives of doxorubicin succinate
A number of lipophilic 14-substituted derivatives of doxorubicin were synthesized through
conjugation of doxorubicin-14-hemisuccinate with different fatty amines or tetradecanol to …
conjugation of doxorubicin-14-hemisuccinate with different fatty amines or tetradecanol to …