Antioxidant defense of Deinococcus radiodurans: how does it contribute to extreme radiation resistance?

I Sadowska-Bartosz, G Bartosz - International Journal of Radiation …, 2023 - Taylor & Francis
Purpose Deinococcus radiodurans is an extremely radioresistant bacterium characterized
by D10 of 10 kGy, and able to grow luxuriantly under chronic ionizing radiation of 60 Gy/h …

Research progress on the biological effects of low-dose radiation in China

K Ji, Y Wang, L Du, C Xu, Y Liu, N He… - Dose …, 2019 - journals.sagepub.com
Human are exposed to ionizing radiation from natural and artificial sources, which
consequently poses a possible risk to human health. However, accumulating evidence …

Ginger Oleoresin Alleviated γ‐Ray Irradiation‐Induced Reactive Oxygen Species via the Nrf2 Protective Response in Human Mesenchymal Stem Cells

K Ji, L Fang, H Zhao, Q Li, Y Shi, C Xu… - Oxidative Medicine …, 2017 - Wiley Online Library
Unplanned exposure to radiation can cause side effects on high‐risk individuals;
meanwhile, radiotherapies can also cause injury on normal cells and tissues surrounding …

Insights into the role of three Endonuclease III enzymes for oxidative stress resistance in the extremely radiation resistant bacterium Deinococcus radiodurans

F Rollo, GD Martins, AG Gouveia, S Ithurbide… - Frontiers in …, 2023 - frontiersin.org
The extremely radiation and desiccation resistant bacterium Deinococcus radiodurans
possesses three genes encoding Endonuclease III-like enzymes (DrEndoIII1, DrEndoIII2 …

Avoidance of protein oxidation correlates with the desiccation and radiation resistance of hot and cold desert strains of the cyanobacterium Chroococcidiopsis

C Fagliarone, C Mosca, I Ubaldi, C Verseux, M Baqué… - Extremophiles, 2017 - Springer
To investigate the relationship between desiccation and the extent of protein oxidation in
desert strains of Chroococcidiopsis a selection of 10 isolates from hot and cold deserts and …

Unraveling the mechanisms of extreme radioresistance in prokaryotes: lessons from nature

A Pavlopoulou, GD Savva, M Louka, PG Bagos… - … Research/Reviews in …, 2016 - Elsevier
The last 50 years, a variety of archaea and bacteria able to withstand extremely high doses
of ionizing radiation, have been discovered. Several lines of evidence suggest a variety of …

DNA Damage Protection for Enhanced Bacterial Survival Under Simulated Low Earth Orbit Environmental Conditions in Escherichia coli

J Puig, N Knödlseder, J Quera, M Algara… - Frontiers in …, 2021 - frontiersin.org
Some organisms have shown the ability to naturally survive in extreme environments, even
outer space. Some of these have natural mechanisms to resist severe DNA damage from …

Application of iChip to grow “uncultivable” microorganisms and its impact on antibiotic discovery

RT Sherpa, CJ Reese… - Journal of Pharmacy & …, 2015 - journals.library.ualberta.ca
Antibiotics have revolutionized modern medicine, allowing significant progress in healthcare
and improvement in life expectancy. Development of antibiotic resistance by pathogenic …

[HTML][HTML] Artesunate enhances radiosensitivity of esophageal cancer cells by inhibiting the repair of DNA damage

Z Fei, W Gu, R **e, H Su, Y Jiang - Journal of Pharmacological Sciences, 2018 - Elsevier
Radiotherapy plays an important therapeutic role in esophageal cancer (EC). However,
acquired radioresistance impairs the efficacy of radiotherapy, often leading to treatment …

[HTML][HTML] Redox status and metabolomic profiling of thioredoxin reductase inhibitors and 4 kGy ionizing radiation-exposed Deinococcus radiodurans

M Sudharsan, NR Prasad, G Kanimozhi… - Microbiological …, 2022 - Elsevier
The gram-positive bacterium Deinococcus radiodurans can survive under extreme ionizing
radiation environment. This study aims to rationalize the role of redox balance, antioxidant …