Emerging roles of the complement system in host–pathogen interactions

SK Sahu, DH Kulkarni, AN Ozanturk, L Ma… - Trends in …, 2022 - cell.com
The complement system has historically been entertained as a fluid-phase, hepatically
derived system which protects the intravascular space from encapsulated bacteria …

Novel evidence on sepsis-inducing pathogens: from laboratory to bedside

S Gatica, B Fuentes, E Rivera-Asín… - Frontiers in …, 2023 - frontiersin.org
Sepsis is a life-threatening condition and a significant cause of preventable morbidity and
mortality globally. Among the leading causative agents of sepsis are bacterial pathogens …

[HTML][HTML] Complement-pentraxins synergy: Navigating the immune battlefield and beyond

YJ Ma, R Parente, H Zhong, Y Sun, C Garlanda… - Biomedicine & …, 2023 - Elsevier
The complement is a crucial immune defense system that triggers rapid immune responses
and offers efficient protection against foreign invaders and unwanted host elements, acting …

[HTML][HTML] Acute phase proteins patterns as biomarkers in bacterial infection: Recent insights

A Al Ali, WS Darwish - Open Veterinary Journal, 2024 - pmc.ncbi.nlm.nih.gov
Escherichia coli is a bacterium with command and pathogenic variants. It has been
implicated in the induction of several inflammatory conditions. Finding a biomarker for …

[HTML][HTML] PTX3 is expressed in terminal lymphatics and shapes their organization and function

A Doni, M Sironi, A Del Prete… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction The lymphatic system is a multifaceted regulator of tissue homeostasis and an
integral part of immune responses. Previous studies had shown that subsets of lymphatic …

The role of pentraxin3 in plasma and bronchoalveolar lavage fluid in COPD patients with invasive pulmonary aspergillosis

Q He, M Zhang, C Feng - BMC Pulmonary Medicine, 2021 - Springer
Background The use of galactomannan (GM) testing in plasma and bronchoalveolar lavage
fluid (BALF) has improved the diagnosis of invasive pulmonary aspergillosis (IPA) in patients …

[HTML][HTML] Convergence of plant sterols and host eukaryotic cell-derived defensive lipids at the infectious pathogen-host interface

D Ghadimi, R Fölster-Holst, S Blömer, M Ebsen… - Biochimie, 2024 - Elsevier
Plant sterols (PSs) exhibit intrinsic functions such as antibacterial effects. Their effects
simultaneously on both host-mediated and bacteria-mediated pathogenesis are not yet fully …

[HTML][HTML] Prognostic Value of Pentraxin3 Protein Expression in Human Malignancies: A Systematic Review and Meta-Analysis

H Jung, J Kang, KM Han, H Kim - Cancers, 2024 - mdpi.com
Abstract Background/Objectives: Pentraxin 3 (PTX3), a member of the pentraxin superfamily,
plays diverse roles in immunity and inflammation. Its dual role in tumorigenesis, exhibiting …

Pentraxin 3 in Myocarditis: Proof-of-Principle Assessment as a Diagnostic and Prognostic Biomarker

A Villatore, A Monno, C Sciorati… - Journal of …, 2024 - Springer
Abstract Pentraxin 3 (PTX3) is an acute phase protein produced in various tissues in
response to microbial and sterile stimuli, which regulates the inflammation outcomes. PTX3 …

[HTML][HTML] PTX3 alleviates hard metal-induced acute lung injury through potentiating efferocytosis

W Yan, D Ma, Y Liu, W Sun, D Cheng, G Li… - Ecotoxicology and …, 2022 - Elsevier
Prolonged exposure to hard metal dust results in hard metal lung disease (HMLD)
characterized by respiratory symptoms. Understanding the pathogenesis and pathological …