Primary hemostasis begins with endothelial injury. VWF, produced by endothelial cells,
binds to platelets and links them to subendothelial collagen. Platelet-derived ADP and …

Arterial and venous thromboses are sustained by development of intraluminal thrombi,
respectively, within the venous and arterial systems. The composition and structure of …

Hemostasis is a complex and tightly regulated process whereby the body attempts to
maintain a homeostatic balance to permit normal blood flow, without bleeding or thrombosis …

Physiological hemostasis is an intricate biological system, where procoagulant and
anticoagulant forces interplay and preserves blood fluidity when blood vessels are intact, or …

Hemostasis is a complex but balanced process that permit normal blood flow, without
adverse events. Disruption of the balance may lead to bleeding or thrombotic events, and …

The investigation of inherited bleeding disorders of secondary hemostasis remains a
challenge for most clinical laboratories, especially those that lack experience or specialized …

Congenital fibrinogen disorders are rare diseases affecting either the quantity
(afibrinogenaemia and hypofibrinogenaemia) or the quality (dysfibrinogenaemia) or both …

This study aimed to provide a preliminary evaluation of the analytical performance of the
new Roche cobas t 711 fully automated coagulation analyzer, which uses both liquid and …

Patients undergoing surgical procedures can bleed for a variety of reasons. Assuming that
the surgical procedure has progressed well and that the surgeon can exclude surgical …

The authors provide a narrative review of mainstream hemostasis analyzers. The review is
presented in two parts. In the first part, the authors give voice to several internationally …