Psychedelic therapies reconsidered: Compounds, clinical indications, and cautious optimism

JM Mitchell, BT Anderson - Neuropsychopharmacology, 2024 - nature.com
The clinical investigation of psychedelic medicines has blossomed over the last 5 years.
Data from a Phase 3 industry trial and a multicenter Phase 2 industry trial, in addition to …

From psychiatry to neurology: Psychedelics as prospective therapeutics for neurodegenerative disorders

U Kozlowska, C Nichols, K Wiatr… - Journal of …, 2022 - Wiley Online Library
The studies of psychedelics, especially psychedelic tryptamines like psilocybin, are rapidly
gaining interest in neuroscience research. Much of this interest stems from recent clinical …

[HTML][HTML] Adverse effects of ayahuasca: Results from the Global Ayahuasca Survey

JC Bouso, Ó Andión, JJ Sarris… - PLOS Global Public …, 2022 - journals.plos.org
Introduction Ayahuasca is a plant-based decoction native to Amazonia, where it has a long
history of use in traditional medicine. Contemporary ritual use of ayahuasca has been …

Ayahuasca's therapeutic potential: What we know–and what not

LO Maia, D Daldegan-Bueno, I Wießner… - European …, 2023 - Elsevier
The therapeutic potential of the psychedelic brew ayahuasca has been investigated in
preclinical and clinical studies. Currently, the most consistent evidence refers to depression …

Changes in mental health, wellbeing and personality following ayahuasca consumption: Results of a naturalistic longitudinal study

D Perkins, BA Pagni, J Sarris, PCR Barbosa… - Frontiers in …, 2022 - frontiersin.org
Background: Naturalistic and placebo-controlled studies suggest ayahuasca, a potent
psychedelic beverage originating from Indigenous Amazonian tradition, may improve mental …

Potential therapeutic effects of an ayahuasca-inspired N, N-DMT and harmine formulation: a controlled trial in healthy subjects

HD Aicher, MJ Mueller, DA Dornbierer, D Suay… - Frontiers in …, 2024 - frontiersin.org
Background There is growing scientific evidence for the therapeutic benefits of the
Amazonian plant-based psychedelic “ayahuasca” for neuropsychiatric disorders such as …

Persisting effects of ayahuasca on empathy, creative thinking, decentering, personality, and well-being

MK Kiraga, NL Mason, MV Uthaug… - Frontiers in …, 2021 - frontiersin.org
Background: Naturalistic and placebo-controlled studies have suggested that ayahuasca, a
traditional Amazonian beverage, could be helpful in the treatment of psychopathologies like …

Influence of context and setting on the mental health and wellbeing outcomes of ayahuasca drinkers: Results of a large international survey

D Perkins, V Schubert, H Simonová, LF Tófoli… - Frontiers in …, 2021 - frontiersin.org
Ayahuasca is a traditional plant decoction containing N, N-dimethyltryptamine (DMT) and
various β-carbolines including harmine, harmaline, and tetrahydroharmine, which has been …

Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of …

K Egger, HD Aicher, P Cumming… - Cellular and Molecular …, 2024 - Springer
The potent hallucinogen N, N-dimethyltryptamine (DMT) has garnered significant interest in
recent years due to its profound effects on consciousness and its therapeutic …

Psychotherapeutic and neurobiological processes associated with ayahuasca: A proposed model and implications for therapeutic use

D Perkins, SGD Ruffell, K Day… - Frontiers in …, 2023 - frontiersin.org
Ayahuasca is a psychoactive Amazonian plant brew. It is usually made from the
Banisteriopsis caapi vine (Spruce ex Griseb. Morton, Malpighiaceae), which contains three …