Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

One of the most frequent statements, provided in different variations in the introduction of
experimental studies on multiple sclerosis (MS), is that “Multiple sclerosis is a demyelinating …

We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG)
antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort. We …

Multiple sclerosis (MS) is a neurological disease characterized by multifocal lesions and
smoldering pathology. Although single-cell analyses provided insights into cytopathology …

A better understanding of the pathological mechanisms that drive neurodegeneration in
individuals with multiple sclerosis is needed to develop therapies that will effectively treat …

Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course,
neuroradiological appearance of the lesions, involvement of susceptibility gene loci, and …

Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are
the end product of a cell lineage which has to undergo a complex and precisely timed …

Microglia harness an unutilized health-promoting potential in age-related
neurodegenerative and neuroinflammatory diseases, conditions like progressive multiple …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …