Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta …
M Huhn, A Nikolakopoulou, J Schneider-Thoma… - The Lancet, 2019 - thelancet.com
Background Schizophrenia is one of the most common, burdensome, and costly psychiatric
disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is …
disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is …
Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017
C Hiemke, N Bergemann, HW Clement… - …, 2018 - thieme-connect.com
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …
Biological insights from 108 schizophrenia-associated genetic loci
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …
alleles, including common alleles of small effect that might be detected by genome-wide …
[HTML][HTML] Biological insights from 108 schizophrenia-associated genetic loci
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …
alleles, including common alleles of small effect that might be detected by genome-wide …
[PDF][PDF] Obesity: definition, comorbidities, causes, and burden
CM Apovian - Am J Manag Care, 2016 - ajmc.s3.amazonaws.com
Body mass index of 30 kg/m2 or higher is used to identify individuals with obesity. In the last
3 decades, the worldwide prevalence of obesity has increased 27.5% for adults and 47.1 …
3 decades, the worldwide prevalence of obesity has increased 27.5% for adults and 47.1 …
Pharmacological management of obesity: an endocrine Society clinical practice guideline
Objective: To formulate clinical practice guidelines for the pharmacological management of
obesity. Participants: An Endocrine Society-appointed Task Force of experts, a …
obesity. Participants: An Endocrine Society-appointed Task Force of experts, a …
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
Background The question of which antipsychotic drug should be preferred for the treatment
of schizophrenia is controversial, and conventional pairwise meta-analyses cannot provide …
of schizophrenia is controversial, and conventional pairwise meta-analyses cannot provide …
Master protocols to study multiple therapies, multiple diseases, or both
J Woodcock, LM LaVange - New England Journal of Medicine, 2017 - Mass Medical Soc
Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
[HTML][HTML] Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care
The lifespan of people with severe mental illness (SMI) is shorter compared to the general
population. This excess mortality is mainly due to physical illness. We report prevalence …
population. This excess mortality is mainly due to physical illness. We report prevalence …
Rethinking schizophrenia
TR Insel - Nature, 2010 - nature.com
How will we view schizophrenia in 2030? Schizophrenia today is a chronic, frequently
disabling mental disorder that affects about one per cent of the world's population. After a …
disabling mental disorder that affects about one per cent of the world's population. After a …