Evolution of the human pathogenic lifestyle in fungi
A Rokas - Nature Microbiology, 2022 - nature.com
Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
Aspergillus fumigatus and aspergillosis: From basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection
Aspergillus fumigatus is an environmental saprobe and opportunistic human fungal
pathogen. Despite an estimated annual occurrence of more than 300,000 cases of invasive …
pathogen. Despite an estimated annual occurrence of more than 300,000 cases of invasive …
Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species
Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of
Virulence Across Aspergillus Species | Genetics | Oxford Academic Skip to Main Content …
Virulence Across Aspergillus Species | Genetics | Oxford Academic Skip to Main Content …
Molecular diagnostics for invasive fungal diseases: Current and future approaches
D Pham, V Sivalingam, HM Tang, JM Montgomery… - Journal of Fungi, 2024 - mdpi.com
Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …
Invasive Aspergillosis and the Impact of Azole-resistance
D Bosetti, D Neofytos - Current Fungal Infection Reports, 2023 - Springer
Purpose of Review IA (invasive aspergillosis) caused by azole-resistant strains has been
associated with higher clinical burden and mortality rates. We review the current …
associated with higher clinical burden and mortality rates. We review the current …
Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States
BN Celia-Sanchez, B Mangum… - Applied and …, 2024 - journals.asm.org
Aspergillus fumigatus is an important global fungal pathogen of humans. Azole drugs are
among the most effective treatments for A. fumigatus infection. Azoles are also widely used …
among the most effective treatments for A. fumigatus infection. Azoles are also widely used …
Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus
The ongoing global pandemic caused by the severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), first described in …
2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), first described in …
Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response
Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen
independent lines of Leishmania mexicana and one L. infantum line were selected for …
independent lines of Leishmania mexicana and one L. infantum line were selected for …
Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens
Fungal pathogens pose an increasingly worrying threat to human health, food security and
ecosystem diversity. To tackle fungal infections and improve current diagnostic and …
ecosystem diversity. To tackle fungal infections and improve current diagnostic and …