The ruminant telomere-to-telomere (rt2t) consortium

TS Kalbfleisch, SD McKay, BM Murdoch, DL Adelson… - Nature …, 2024 - nature.com
Abstract Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and
function of the previously 'invisible'parts of the genome and allow comparative analyses of …

From FAANG to fork: application of highly annotated genomes to improve farmed animal production

EL Clark, AL Archibald, HD Daetwyler, MAM Groenen… - Genome Biology, 2020 - Springer
The Food and Agriculture Organisation of the United Nations (FAO) reports that by the year
2050 the global human population is likely to reach 9.7 billion, rising to 11.2 billion by 2100 …

Pig genome functional annotation enhances the biological interpretation of complex traits and human disease

Z Pan, Y Yao, H Yin, Z Cai, Y Wang, L Bai… - Nature …, 2021 - nature.com
The functional annotation of livestock genomes is crucial for understanding the molecular
mechanisms that underpin complex traits of economic importance, adaptive evolution and …

Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research

C Kern, Y Wang, X Xu, Z Pan, M Halstead… - Nature …, 2021 - nature.com
Gene regulatory elements are central drivers of phenotypic variation and thus of critical
importance towards understanding the genetics of complex traits. The Functional Annotation …

An improved pig reference genome sequence to enable pig genetics and genomics research

A Warr, N Affara, B Aken, H Beiki, DM Bickhart… - …, 2020 - academic.oup.com
Abstract Background The domestic pig (Sus scrofa) is important both as a food source and
as a biomedical model given its similarity in size, anatomy, physiology, metabolism …

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription

L **, Q Tang, S Hu, Z Chen, X Zhou, B Zeng… - Nature …, 2021 - nature.com
A comprehensive transcriptomic survey of pigs can provide a mechanistic understanding of
tissue specialization processes underlying economically valuable traits and accelerate their …

An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics

Z Pan, Y Wang, M Wang, Y Wang, X Zhu, S Gu… - Science …, 2023 - science.org
A comprehensive characterization of regulatory elements in the chicken genome across
tissues will have substantial impacts on both fundamental and applied research. Here, we …

Genome structures resolve the early diversification of teleost fishes

E Parey, A Louis, J Montfort, O Bouchez, C Roques… - Science, 2023 - science.org
Accurate species phylogenies are a prerequisite for all evolutionary research. Teleosts are
the largest and most diversified group of extant vertebrates, but relationships among their …

Twelve quick steps for genome assembly and annotation in the classroom

H Jung, T Ventura, JS Chung, WJ Kim… - PLoS computational …, 2020 - journals.plos.org
Eukaryotic genome sequencing and de novo assembly, once the exclusive domain of well-
funded international consortia, have become increasingly affordable, thus fitting the budgets …

Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing

J Herrera-Uribe, JE Wiarda, SK Sivasankaran… - Frontiers in …, 2021 - frontiersin.org
Pigs are a valuable human biomedical model and an important protein source supporting
global food security. The transcriptomes of peripheral blood immune cells in pigs were …