Global epidemiology of cirrhosis—aetiology, trends and predictions

DQ Huang, NA Terrault, F Tacke, LL Gluud… - Nature reviews …, 2023 - nature.com
Cirrhosis is an important cause of morbidity and mortality in people with chronic liver
disease worldwide. In 2019, cirrhosis was associated with 2.4% of global deaths. Owing to …

[HTML][HTML] Exercise as medicine for depressive symptoms? A systematic review and meta-analysis with meta-regression

A Heissel, D Heinen, LL Brokmeier… - British journal of sports …, 2023 - bjsm.bmj.com
Objective To estimate the efficacy of exercise on depressive symptoms compared with non-
active control groups and to determine the moderating effects of exercise on depression and …

Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study

GA Gregory, TIG Robinson, SE Linklater… - The lancet Diabetes & …, 2022 - thelancet.com
Background Accurate data on type 1 diabetes prevalence, incidence, associated mortality
and life expectancy are crucial to inform public health policy, but these data are scarce. We …

Global epidemiology of rheumatoid arthritis

A Finckh, B Gilbert, B Hodkinson, SC Bae… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Overcoming barriers to patient adherence: the case for develo** innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Major depressive disorder: hypothesis, mechanism, prevention and treatment

L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - Signal transduction and …, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta …

H Yao, A Zhang, D Li, Y Wu, CZ Wang, JY Wan… - bmj, 2024 - bmj.com
Objective To evaluate the comparative efficacy and safety of glucagon-like peptide-1
receptor agonists (GLP-1RAs) on glycaemic control, body weight, and lipid profile in adults …

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2019

X Li, X Feng, X Sun, N Hou, F Han… - Frontiers in aging …, 2022 - frontiersin.org
Background With the increase in the aging population worldwide, Alzheimer's disease has
become a rapidly increasing public health concern. Monitoring the dementia disease burden …

Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

BS Sheena, L Hiebert, H Han, H Ippolito… - The lancet …, 2022 - thelancet.com
Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …