Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents

TJ Clough, L Jiang, KL Wong, NJ Long - Nature communications, 2019 - nature.com
Gadolinium (III) complexes have been widely utilised as magnetic resonance imaging (MRI)
contrast agents for decades. In recent years however, concerns have developed about their …

Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging

A Gupta, P Caravan, WS Price… - Inorganic …, 2020 - ACS Publications
Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

Gadolinium deposition and the potential for toxicological sequelae–A literature review of issues surrounding gadolinium‐based contrast agents

KA Layne, PI Dargan, JRH Archer… - British journal of clinical …, 2018 - Wiley Online Library
Every year, approximately 30 million magnetic resonance imaging scans are enhanced with
gadolinium‐based contrast agents (GBCAs) worldwide. Although the development of …

Manganese‐based functional nanoplatforms: Nanosynthetic construction, physiochemical property, and theranostic applicability

X Qian, X Han, L Yu, T Xu… - Advanced Functional …, 2020 - Wiley Online Library
Transition metal‐based nanoparticles have shown their broad applications in versatile
biomedical applications. Although traditional iron‐based nanoparticles have been …

Strategies to perform magnetic resonance imaging in infants and young children without sedation

SG Harrington, C Jaimes, KM Weagle, MLC Greer… - Pediatric …, 2022 - Springer
Given the increasing use of MRI in the pediatric population, the need for sedation in MRI
performed in young children is a topic of growing importance. Although sedation is generally …

Rare earth smart nanomaterials for bone tissue engineering and implantology: Advances, challenges, and prospects

D Natarajan, Z Ye, L Wang, L Ge… - Bioengineering & …, 2022 - Wiley Online Library
Bone grafts or prosthetic implant designing for clinical application is challenging due to the
complexity of integrated physiological processes. The revolutionary advances of …

[HTML][HTML] Cardiomyopathy in Duchenne Muscular Dystrophy and the Potential for Mitochondrial Therapeutics to Improve Treatment Response

S Gandhi, HL Sweeney, CC Hart, R Han, CGR Perry - Cells, 2024 - mdpi.com
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by
mutations to the dystrophin gene, resulting in deficiency of dystrophin protein, loss of …

Gadolinium-based contrast agents—review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on …

E Blumfield, DW Swenson, RS Iyer, AL Stanescu - Pediatric radiology, 2019 - Springer
Gadolinium has been used as a base for contrast agents in MRI for the last three decades.
Numerous studies over the last 4 years have reported increased signal intensity in deep …

Composed in the f-block: solution structure and function of kinetically inert lanthanide (III) complexes

LG Nielsen, AKR Junker, TJ Sørensen - Dalton transactions, 2018 - pubs.rsc.org
It has been more than 15 years since the last authoritative report on the solution structure of
lanthanide complexes made from cylcen derived polydentate ligands. The field has …