[HTML][HTML] Mechanisms of aortic dissection: from pathological changes to experimental and in silico models

M Rolf-Pissarczyk, R Schussnig, TP Fries… - Progress in Materials …, 2024 - Elsevier
Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

Cardiovascular models for personalised medicine: Where now and where next?

DR Hose, PV Lawford, W Huberts, LR Hellevik… - Medical engineering & …, 2019 - Elsevier
The aim of this position paper is to provide a brief overview of the current status of
cardiovascular modelling and of the processes required and some of the challenges to be …

Evaluation and verification of patient-specific modelling of type B aortic dissection

CH Armour, B Guo, S Saitta, S Pirola, Y Liu… - Computers in biology …, 2022 - Elsevier
Quantitative assessment of the complex hemodynamic environment in type B aortic
dissection (TBAD) through computational fluid dynamics (CFD) simulations can provide …

Calibration of patient-specific boundary conditions for coupled CFD models of the aorta derived from 4D Flow-MRI

SMD Black, C Maclean, P Hall Barrientos… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Patient-specific computational fluid dynamics (CFD) models permit analysis of
complex intra-aortic hemodynamics in patients with aortic dissection (AD), where vessel …

Association of hemodynamic factors and progressive aortic dilatation following type A aortic dissection surgical repair

Y Zhu, S Mirsadraee, G Asimakopoulos, A Gambaro… - Scientific Reports, 2021 - nature.com
Type A aortic dissection (TAAD) involves the ascending aorta or the arch. Acute TAAD
usually requires urgent replacement of the ascending aorta. However, a subset of these …

A Combined In Vivo, In Vitro, In Silico Approach for Patient-Specific Haemodynamic Studies of Aortic Dissection

M Bonfanti, G Franzetti, S Homer-Vanniasinkam… - Annals of biomedical …, 2020 - Springer
The optimal treatment of Type-B aortic dissection (AD) is still a subject of debate, with up to
50% of the cases develo** late-term complications requiring invasive intervention. A …

The influence of minor aortic branches in patient-specific flow simulations of type-B aortic dissection

C Stokes, F Haupt, D Becker, V Muthurangu… - Annals of biomedical …, 2023 - Springer
Type-B aortic dissection (TBAD) is a disease in which a tear develops in the intimal layer of
the descending aorta forming a true lumen and false lumen (FL). Because disease …

An integrated fluid–structure interaction and thrombosis model for type B aortic dissection

MY Chong, B Gu, CH Armour, S Dokos, ZC Ong… - … and modeling in …, 2022 - Springer
False lumen thrombosis (FLT) in type B aortic dissection has been associated with the
progression of dissection and treatment outcome. Existing computational models mostly …

Effect of intimal flap motion on flow in acute type B aortic dissection by using fluid‐structure interaction

MY Chong, B Gu, BT Chan, ZC Ong… - … journal for numerical …, 2020 - Wiley Online Library
A monolithic, fully coupled fluid‐structure interaction (FSI) computational framework was
developed to account for dissection flap motion in acute type B aortic dissection (TBAD) …

[HTML][HTML] Experimental evaluation of the patient-specific haemodynamics of an aortic dissection model using particle image velocimetry

G Franzetti, M Bonfanti, S Homer-Vanniasinkam… - Journal of …, 2022 - Elsevier
Aortic Dissection (AD) is a complex pathology that affects the aorta. Diagnosis, management
and treatment remain a challenge as it is a highly patient-specific pathology and there is still …