A pangenome is composed of all the genetic variability of a group of individuals, and its
application to the study of neurodegenerative diseases may provide valuable insights into …

This review provides a comprehensive overview of the role of G9a/EHMT2, focusing on its
structure and exploring the impact of its pharmacological and/or gene inhibition in various …

Healthcare is an emerging industry with significant market potential in the 21st century.
Therefore, this study aimed to evaluate the benefits of tube feeding Huáng qí and its …

Neuropathological aging is associated with memory impairment and cognitive decline,
affecting several brain areas including the neurogenic niche of the dentate gyrus of the …

Epigenetic alterations are a fundamental pathological hallmark of Alzheimer's disease (AD).
Herein, we show the upregulation of G9a and H3K9me2 in the brains of AD patients …

Alzheimer's disease (AD) is the most common age-related neurodegenerative disease
characterized by memory loss and cognitive impairment. The causes of the disease are not …

Pearls have been used in traditional Chinese medicine for the treatment of myopia, epilepsy,
and palpitations. We previously demonstrated that the intraperitoneal administration of nacre …

Alzheimer's disease (AD) is a worldwide problem. Currently, there are no effective drugs for
AD treatment. Scrophularia buergeriana Miquel (SB) is a traditional herbal medicine used in …

Dysregulation of G9a, a histone-lysine N-methyltransferase, has been observed in
Alzheimer's disease and has been correlated with increased levels of chronic inflammation …

G9a, a histone lysine methyltransferase, is instrumental in regulating gene expression
through epigenetic modifications. Its overexpression is closely linked to the progression of …