The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review

K Liu, M Zheng, R Lu, J Du, Q Zhao, Z Li, Y Li… - Cancer cell …, 2020 - Springer
One of the most prominent features of tumor cells is uncontrolled cell proliferation caused by
an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives …

Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis

MA Morelli, PE Cohen - Reproduction, 2005 - rep.bioscientifica.com
The study of mammalian meiosis is complicated by the timing of meiotic events in females
and by the intermingling of meiotic sub-stages with somatic cells in the gonad of both sexes …

Platelet-rich plasma enhances the proliferation of human adipose stem cells through multiple signaling pathways

F Lai, N Kakudo, N Morimoto, S Taketani… - Stem cell research & …, 2018 - Springer
Background Platelet-rich plasma (PRP) is an autologous blood product that contains a high
concentration of several growth factors. Platelet-derived growth factor (PDGF)-BB is a …

[HTML][HTML] Ca2+-induced mitochondrial ROS regulate the early embryonic cell cycle

Y Han, S Ishibashi, J Iglesias-Gonzalez, Y Chen… - Cell reports, 2018 - cell.com
While it is appreciated that reactive oxygen species (ROS) can act as second messengers in
both homeostastic and stress response signaling pathways, potential roles for ROS during …

Greatwall maintains mitosis through regulation of PP2A

S Vigneron, E Brioudes, A Burgess, JC Labbé… - The EMBO …, 2009 - embopress.org
Greatwall (GW) is a new kinase that has an important function in the activation and the
maintenance of cyclin B–Cdc2 activity. Although the mechanism by which it induces this …

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375. S2 cells

CCC Wang, YM Chiang, SC Sung, YL Hsu, JK Chang… - Cancer letters, 2008 - Elsevier
This study is the first to investigate the anticancer effect of plumbagin in human melanoma
A375. S2 cells. Plumbagin exhibited effective cell growth inhibition by inducing cancer cells …

Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase

CG Liang, YQ Su, HY Fan, H Schatten… - Molecular …, 2007 - academic.oup.com
Oocyte meiotic maturation is one of the important physiological requirements for species
survival. However, little is known about the detailed events occurring during this process. A …

[HTML][HTML] Whole-genome sequencing to identify candidate genes for litter size and to uncover the variant function in goats (Capra hircus)

K Wang, X Liu, T Qi, Y Hui, H Yan, L Qu, X Lan, C Pan - Genomics, 2021 - Elsevier
To select candidate genes for goat prolificacy, we managed six multi-and six single-kid
female goats at the same feeding level and in the same management mode over a 4-year …

[HTML][HTML] Inhibition of cell proliferation and metastasis by scutellarein regulating PI3K/Akt/NF-κB signaling through PTEN activation in hepatocellular carcinoma

SE Ha, SM Kim, P Vetrivel, HH Kim… - International journal of …, 2021 - mdpi.com
Scutellarein (SCU) is a well-known flavone with a broad range of biological activities against
several cancers. Human hepatocellular carcinoma (HCC) is major cancer type due to its …

Protein phosphatase 1 is a key player in nuclear events

S Rebelo, M Santos, F Martins, EFC e Silva… - Cellular signalling, 2015 - Elsevier
Reversible protein phosphorylation at serine (Ser), threonine (Thr) and tyrosine (Tyr)
residues is among the major regulatory mechanism in eukaryotic cells. The eukaryotic …