Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics

R Thapa, M Afzal, A Goyal, G Gupta, AA Bhat… - Life sciences, 2024 - Elsevier
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …

Exosomal ncRNAs in liquid biopsies for lung cancer

MS Hussain, G Gupta, N Ghaboura, E Moglad… - Clinica chimica acta, 2024 - Elsevier
Exosomal non-coding RNAs (ncRNAs) have become essential contributors to advancing
and treating lung cancers (LCs). The development of liquid biopsies that utilize exosomal …

Unlocking the secrets: Volatile Organic Compounds (VOCs) and their devastating effects on lung cancer

MS Hussain, G Gupta, R Mishra, N Patel… - … -Research and Practice, 2024 - Elsevier
Lung cancer (LCs) is still a serious health problem globally, with many incidences attributed
to environmental triggers such as Volatile Organic Compounds (VOCs). VOCs are a broad …

Deciphering NF-kappaB pathways in smoking-related lung carcinogenesis

R Thapa, E Moglad, A Goyal, AA Bhat… - EXCLI …, 2024 - pmc.ncbi.nlm.nih.gov
One of the main causes of death worldwide is lung cancer, which is largely caused by
cigarette smoking. The crucial transcription factor NF-κB, which controls inflammatory …

ST8SIA6-AS1, a novel lncRNA star in liver cancer

C Qiu, H Fan, S Tao, Z Deng, H Luo… - Frontiers in Cell and …, 2024 - frontiersin.org
Liver cancer is one of the most lethal gastrointestinal malignancies. Emerging evidence has
underscored the pivotal role of long non-coding RNAs (lncRNAs) in tumorigenesis, with …

[HTML][HTML] The impact of formaldehyde exposure on lung inflammatory disorders: Insights into asthma, bronchitis, and pulmonary fibrosis

AA Bhat, M Afzal, A Goyal, G Gupta, R Thapa… - Chemico-biological …, 2024 - Elsevier
Lung inflammatory disorders are a major global health burden, impacting millions of people
and raising rates of morbidity and death across many demographic groups. An industrial …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

ncRNAs and Their Impact on Dopaminergic Neurons: Autophagy Pathways in Parkinson's Disease

R Thapa, E Moglad, M Afzal, G Gupta, AA Bhat… - Ageing Research …, 2024 - Elsevier
Parkinson's Disease (PD) is a complex neurological illness that causes severe motor and
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …

Non-coding RNAs as key regulators of Gasdermin-D mediated pyroptosis in cancer therapy

G Gupta, M Afzal, E Moglad, H Ali, TG Singh… - … -Research and Practice, 2024 - Elsevier
Pyroptosis is an inflammatory programed cell death process that plays a crucial role in
cancer therapeutic, while Gasdermin-D is a critical effector protein for pyroptosis execution …

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

MS Hussain, E Moglad, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …