The emergence of infectious diseases promises to be one of the leading mortality factors in
the healthcare sector. Although several drugs are available on the market, newly found …

Lower and upper respiratory infections are the fourth highest cause of global mortality.
Epidemic and pandemic outbreaks of respiratory infection are a major medical concern …

Background In 2000, seven-valent pneumococcal conjugate vaccine (PCV7) was introduced
in the USA and resulted in dramatic reductions in invasive pneumococcal disease (IPD) and …

Bacterial interspecies interactions play clinically important roles in sha** microbial
community composition. We observed that Corynebacterium spp. are overrepresented in …

To overview the present global burden of pneumococcal disease is important because new
preventive measures such as the pneumococcal conjugate vaccine 13 are currently being …

Abstract Background Pneumococcal conjugate vaccines (PCVs) have greatly reduced the
incidence of pneumococcal disease, yet unmet medical need remains due to increased …

Streptococcus pneumoniae (the pneumoccus) is the leading cause of otitis media,
community-acquired pneumonia, and bacterial meningitis. The success of the …

Streptococcus pneumoniae is an important global pathogen that causes a wide range of
clinical disease in children and adults. Pneumococcal pneumonia is by far the common …

Vaccines save thousands of lives in the United States every year, but many adults remain
unvaccinated. Low rates of vaccine uptake lead to costs to individuals and society in terms of …

Pneumococcal polysaccharide vaccines (PPVs) and conjugate vaccines (PCVs), of which
PPV23 and PCV13 are the current front runners, have had a significant, beneficial impact on …