The second near-infrared (NIR-II) fluorescence imaging (FLI) has been widely studied for its
advantages of low self-fluorescence, strong tissue penetration, and high resolution. In recent …

Lactate oxidase (LOX) is a natural enzyme that efficiently consumes lactate. In the presence
of oxygen, LOX can catalyse the formation of pyruvate and hydrogen peroxide (H2O2) from …

Pancreatic cancer is a highly fatal disease, and existing treatment methods are ineffective,
so it is urgent to develop new effective treatment strategies. The high dependence of …

The overexpressed extracellular matrix and elevated interstitial fluid pressure in tumor
extremely restricts deep infiltration of nanomedicines, which makes poor penetration an …

Tumor relapse and metastasis become a big challenge in treating malignant melanoma
because conventional therapeutic options often fail to eradicate the tumor residue after …

Despite the promising clinical applications of immunotherapy, its effectiveness is often
limited by low immune responses and tumor immune escape. In this study, we introduce a …

Due to the rapid progression and aggressive metastasis of breast cancer, its diagnosis and
treatment remain a great challenge. The simultaneous inhibition of tumor growth and …

Infected wound healing is obstructed by not only bacterial infection, but also the formation of
bacterial biofilm. Over the past decades, researchers have developed a large number of …

To simplify the composition and improve the efficacy of metal-phenolic network (MPN)-
based nanomedicine, herein, we designed an MPN platform to deliver programmed death …

The vesicle, which consists of the cytoplasm encapsulated by the lipid bilayer, has acted as
an important mediator of intercellular communication as a potential tool for disease …