Systemic immunoglobulin light chain amyloidosis

G Merlini, A Dispenzieri, V Sanchorawala… - Nature reviews Disease …, 2018 - nature.com
Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by
the conversion of immunoglobulin light chains from their soluble functional states into highly …

Secondary, AA, amyloidosis

R Papa, HJ Lachmann - Rheumatic Disease Clinics, 2018 - rheumatic.theclinics.com
Secondary, AA, amyloidosis is a rare systemic complication that can develop in any long-
term inflammatory disorder, characterized by the pathogenic extracellular deposition of …

Global epidemiology of amyloid light-chain amyloidosis

N Kumar, NJ Zhang, D Cherepanov… - Orphanet Journal of …, 2022 - Springer
Background Amyloid light-chain (AL) amyloidosis is an ultra-rare disease associated with
significant morbidity and mortality. Few studies have examined the global epidemiology of …

Venetoclax induces deep hematologic remissions in t (11; 14) relapsed/refractory AL amyloidosis

VJ Premkumar, S Lentzsch, S Pan, D Bhutani… - Blood cancer …, 2021 - nature.com
Venetoclax is efficacious in relapsed/refractory t (11; 14) multiple myeloma, thus warranting
investigation in light-chain amyloidosis (AL). This retrospective cohort includes 43 patients …

Incidence of AL amyloidosis in Olmsted County, Minnesota, 1990 through 2015

RA Kyle, DR Larson, PJ Kurtin, S Kumar… - Mayo Clinic …, 2019 - Elsevier
Objective To determine the incidence of immunoglobulin light chain amyloidosis (AL
amyloidosis) in a strictly defined geographic area from 1990 through 2015. Patients and …

[HTML][HTML] Gastrointestinal amyloidosis: review of the literature

K Rowe, J Pankow, F Nehme, W Salyers - Cureus, 2017 - ncbi.nlm.nih.gov
Gastrointestinal amyloidosis (GIA), a protein deposition disorder, represents a complex
common pathway that encompasses multiple etiologies and presentations. It represents a …

A population-based cohort study of the epidemiology of light-chain amyloidosis in Taiwan

HA Hou, CH Tang, CH Goh, SP Shen, KC Huang… - Scientific Reports, 2022 - nature.com
The incidence rate of AL (light-chain) amyloidosis is not known in Asia. We conducted a
retrospective cohort study using the Taiwan National Healthcare Insurance Research …

Systemic amyloidosis journey from diagnosis to outcomes: a twelve-year real-world experience of a single center in a middle-income country

RS Szor, F Fernandes, AMM Lino… - Orphanet Journal of …, 2022 - Springer
Background Systemic amyloidosis is caused by the deposition of misfolded protein
aggregates in tissues, leading to progressive organ dysfunction and death. Epidemiological …

Treatment patterns and outcomes in light chain amyloidosis: An institutional registry of amyloidosis report in Argentina

ML Posadas-Martinez, MA Aguirre, E Brulc, MS Saez… - PLoS …, 2022 - journals.plos.org
Light chain (AL) amyloidosis is a form of systemic amyloidosis, causing organ dysfunction,
mainly affecting the heart and kidney. Patient-tailored and risk-adapted decision making is …

Análisis descriptivo de 4776 pacientes internados en servicios de clínica médica POR COVID-19. Resultados del Registro Multicéntrico Argentino-REMA-COVID-19

BR Boietti, M Mirofsky, R Valentini… - Medicina (Buenos …, 2021 - SciELO Argentina
Se realizó un registro multicéntrico que incluyó personas adultas internadas por COVID-19
en varias provincias de la Argentina, desde marzo a octubre de 2020. Los objetivos fueron …