Importance Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer
each year, including 1.6 million people in the United States. These ulcers precede 80% of …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the management and prevention of diabetes‐related foot …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Aim The diagnosis, severity and extent of a sterile inflammation or a septic infection could be
challenging since there is not one single test able to achieve an accurate diagnosis. The …

At least half of all amputations occur in people with diabetes, most commonly because of an
infected diabetic foot ulcer. A thorough understanding of the causes and management of …

Osteomyelitis is an inflammatory condition of bone secondary to an infectious process.
Osteomyelitis is usually clinically diagnosed with support from imaging and laboratory …

Diabetic foot infection is the leading cause of non-traumatic lower limb amputations
worldwide. In addition, diabetes mellitus and sequela of the disease are increasing in …

Background Securing an early accurate diagnosis of diabetic foot infections and assessment
of their severity are of paramount importance since these infections can cause great …

Importance Traditional approaches to practice guidelines frequently result in dissociation
between strength of recommendation and quality of evidence. Objective To construct a …