Do we need a third mechanistic descriptor for chronic pain states?

E Kosek, M Cohen, R Baron, GF Gebhart, JA Mico… - Pain, 2016 - journals.lww.com
The redefinition of neuropathic pain, 23 which specifically excludes the concept of
“dysfunction,” has left a large group of patients without a valid pathophysiological descriptor …

Central sensitization: implications for the diagnosis and treatment of pain

CJ Woolf - pain, 2011 - Elsevier
Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and
synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central …

Brain morphometric changes in fibromyalgia and the impact of psychometric and clinical factors: a volumetric and diffusion-tensor imaging study

B Mosch, V Hagena, S Herpertz, M Diers - Arthritis Research & Therapy, 2023 - Springer
Background Previous studies have repeatedly found distinct brain morphometric changes in
patients with fibromyalgia (FM), mainly affecting gray and white matter abnormalities in …

[HTML][HTML] Focal modulation of the primary motor cortex in fibromyalgia using 4× 1-ring high-definition transcranial direct current stimulation (HD-tDCS): immediate and …

MF Villamar, P Wivatvongvana, J Patumanond… - The Journal of …, 2013 - Elsevier
Fibromyalgia is a prevalent chronic pain syndrome characterized by altered pain and
sensory processing in the central nervous system, which is often refractory to multiple …

Fibromyalgia and depression

RH Gracely, M Ceko… - Pain research and …, 2012 - Wiley Online Library
Fibromyalgia and depression might represent two manifestations of affective spectrum
disorder. They share similar pathophysiology and are largely targeted by the same drugs …

Efficacy of anodal transcranial direct current stimulation (tDCS) for the treatment of fibromyalgia: results of a randomized, sham-controlled longitudinal clinical trial

A Valle, S Roizenblatt, S Botte, S Zaghi… - Journal of pain …, 2009 - pmc.ncbi.nlm.nih.gov
Fibromyalgia has been recognized as a central pain disorder with evidence of
neuroanatomic and neurophysiologic alterations. Previous studies with techniques of …

[HTML][HTML] Clinically effective treatment of fibromyalgia pain with high-definition transcranial direct current stimulation: phase II open-label dose optimization

L Castillo-Saavedra, N Gebodh, M Bikson… - The Journal of …, 2016 - Elsevier
Despite promising preliminary results in treating fibromyalgia (FM) pain, no neuromodulation
technique has been adopted in clinical practice because of limited efficacy, low response …

Overall comorbidities in functional neurological disorder: a narrative review

G Carle-Toulemonde, J Goutte, N Do-Quang-Cantagrel… - L'encephale, 2023 - Elsevier
Introduction The importance to assess and include the frequent comorbidities in the
personalised care management plan of patients with functional neurological disorders …

[PDF][PDF] Effectiveness and safety of transcranial direct current stimulation in fibromyalgia: a systematic review and meta-analysis.

CE Zhu, YU Bo, W Zhang, C Wen-Hua… - Journal of …, 2017 - dengg-med.at
Objective: To evaluate the effectiveness and safety of transcranial direct current stimulation
for fibro myalgia. Methods: Databases, conference records and re gistered trials were …

[HTML][HTML] Clinical manifestations of body memories: The impact of past bodily experiences on mental health

A Gentsch, E Kuehn - Brain sciences, 2022 - mdpi.com
Bodily experiences such as the feeling of touch, pain or inner signals of the body are deeply
emotional and activate brain networks that mediate their perception and higher-order …