Atopic dermatitis (AD) is a common yet complex skin disease, posing a therapeutic
challenge with increasingly recognized different phenotypes among variable patient …

Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disease with a wide range of
heterogeneity. Accurate biomarkers or predictors are the keys to instructing personalized …

Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper
understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic …

Background Our current understanding of atopic dermatitis (AD) and psoriasis
pathophysiology is largely derived from skin biopsy studies that cause scarring and may be …

Abundant heterogeneous immune cells infiltrate lesions in chronic inflammatory diseases
and characterization of these cells is needed to distinguish disease-promoting from …

Atopic dermatitis (AD) is a highly heterogeneous inflammatory disease regarding both its
pathophysiology and clinical manifestations. However, it is treated according to the “one …

Allergies are typically endemic, complex and heterogeneous diseases with a high impact at
quality of life. Mechanistically, type 2 immune responses involving eosinophil and basophil …

Psoriasis is an IL-23/Th17-mediated skin disorder with a strong genetic predisposition. The
impact of its susceptibility gene nitric oxide synthase 2 (NOS2) remains unknown. Here, we …

Clinical overlaps between psoriasis and atopic dermatitis (AD) are sometimes undiscernible,
and there is no consensus on whether to treat the overlap phenotype as psoriasis or AD. We …

About 20% of the general population is contact-sensitized to common haptens such as
fragrances, preservatives, and metals. Many also develop allergic contact dermatitis (ACD) …