Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

Low luminance visual acuity as a clinical measure and clinical trial outcome measure: a sco** review

LJ Wood, JK Jolly, TMW Buckley… - Ophthalmic and …, 2021 - Wiley Online Library
Purpose The measurement of standard visual acuity (VA) is the most well‐known part of any
ophthalmic examination to indicate visual function. Despite this, it is insensitive in detecting …

Microbiota mitochondria disorders as hubs for early age-related macular degeneration

J Fehér, Á Élő, L István, ZZ Nagy, Z Radák, G Scuderi… - Geroscience, 2022 - Springer
Age-related macular degeneration (AMD) is a progressive neurodegenerative disease
affecting the central area (macula lutea) of the retina. Research on the pathogenic …

Artificial intelligence in age-related macular degeneration: state of the art and recent updates

E Crincoli, R Sacconi, L Querques, G Querques - BMC ophthalmology, 2024 - Springer
Age related macular degeneration (AMD) represents a leading cause of vision loss and it is
expected to affect 288 million people by 2040. During the last decade, machine learning …

AI-based structure-function correlation in age-related macular degeneration

L von der Emde, M Pfau, FG Holz, M Fleckenstein… - Eye, 2021 - nature.com
Sensitive and robust outcome measures of retinal function are pivotal for clinical trials in age-
related macular degeneration (AMD). A recent development is the implementation of …

Accurate drusen segmentation in optical coherence tomography via order-constrained regression of retinal layer heights

O Morelle, MWM Wintergerst, RP Finger, T Schultz - Scientific Reports, 2023 - nature.com
Drusen are an important biomarker for age-related macular degeneration (AMD). Their
accurate segmentation based on optical coherence tomography (OCT) is therefore relevant …

[HTML][HTML] Heterogenous visual function deficits in intermediate age-related macular degeneration–A MACUSTAR report

HMP Dunbar, DP Crabb, C Behning, AM Binns… - Ophthalmology …, 2025 - Elsevier
Objective To examine the extent to which visual function in Beckman age-related macular
degeneration (AMD) disease stages differ from age similar peers with no AMD and using …

[HTML][HTML] Spatial cluster patterns of retinal sensitivity loss in intermediate age-related macular degeneration features

M Trinh, M Kalloniatis… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: To examine spatial patterns of retinal sensitivity loss in the three key features of
intermediate age-related macular degeneration (iAMD). Methods: One-hundred individuals …

[HTML][HTML] Exploring reticular pseudodrusen extent and impact on mesopic visual sensitivity in intermediate age-related macular degeneration

H Kumar, RH Guymer, LAB Hodgson… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: To explore the impact of the extent of reticular pseudodrusen (RPD) on mesopic
visual sensitivity in individuals with intermediate age-related macular degeneration (AMD) …

[HTML][HTML] Longitudinal evaluation of visual function impairments in early and intermediate age-related macular degeneration patients

EM Lad, V Fang, M Tessier, A Rautanen, J Gayan… - Ophthalmology …, 2022 - Elsevier
Purpose To evaluate visual function (VF) changes in early and intermediate age-related
macular degeneration (eAMD and iAMD) over 24 months. Design Prospective …