Recent advances in asymmetric borylation by transition metal catalysis

J Hu, M Ferger, Z Shi, TB Marder - Chemical Society Reviews, 2021 - pubs.rsc.org
Chiral organoboronates have played a critical role in organic chemistry and in the
development of materials science and pharmaceuticals. Much effort has been devoted to …

Recent strategies in the nucleophilic dearomatization of pyridines, quinolines, and isoquinolines

M Escolano, D Gaviña, G Alzuet-Piña… - Chemical …, 2024 - ACS Publications
Dearomatization reactions have become fundamental chemical transformations in organic
synthesis since they allow for the generation of three-dimensional complexity from two …

Copper-boryl mediated organic synthesis

D Hemming, R Fritzemeier, SA Westcott… - Chemical Society …, 2018 - pubs.rsc.org
Organoboron compounds are valuable synthetic intermediates that find application in a
diverse variety of processes including both C–X and C–C bond-forming transformations …

Copper-catalyzed functionalization of 1, 3-dienes: hydrofunctionalization, borofunctionalization, and difunctionalization

GJP Perry, T Jia, DJ Procter - ACS Catalysis, 2019 - ACS Publications
The catalytic conversion of chemical feedstocks into products of medicinal and agricultural
value is a key theme across modern synthetic chemistry. As 1, 3-dienes are readily available …

Sha** molecular landscapes: recent advances, opportunities, and challenges in dearomatization

CJ Huck, D Sarlah - Chem, 2020 - cell.com
Dearomatization is a fundamental chemical transformation, and it underlies some of the
most efficient tactics for generating three-dimensional complexity from basic two …

Asymmetric synthesis of secondary and tertiary boronic esters

BSL Collins, CM Wilson, EL Myers… - Angewandte Chemie …, 2017 - Wiley Online Library
Non‐racemic chiral boronic esters are recognised as immensely valuable building blocks in
modern organic synthesis. Their stereospecific transformation into a variety of functional …

Catalytic enantio-and regioselective addition of nucleophiles in the intermolecular hydrofunctionalization of 1, 3-dienes

NJ Adamson, SJ Malcolmson - ACS Catalysis, 2019 - ACS Publications
Catalytic enantioselective synthesis of small-molecule building blocks with allylic
stereogenic centers is an important objective in organic synthesis, but preparing this motif …

Oxidative dearomatization of pyridines

Z Siddiqi, TW Bingham, T Shimakawa… - Journal of the …, 2024 - ACS Publications
Dearomatization of pyridines is a well-established synthetic approach to access piperidines.
Although remarkably powerful, existing dearomatization processes have been limited to the …

Highly Selective and Catalytic Generation of Acyclic Quaternary Carbon Stereocenters via Functionalization of 1,3-Dienes with CO2

XW Chen, L Zhu, YY Gui, K **g, YX Jiang… - Journal of the …, 2019 - ACS Publications
The catalytic asymmetric functionalization of readily available 1, 3-dienes is highly important,
but current examples are mostly limited to the construction of tertiary chiral centers. The …

Regio‐and Diastereoselective Synthesis of Polysubstituted Piperidines Enabled by Boronyl Radical‐Catalyzed (4+ 2) Cycloaddition

Z Ding, Z Wang, Y Wang, X Wang, Y Xue… - Angewandte …, 2024 - Wiley Online Library
Piperidines are widely present in small molecule drugs and natural products. Despite many
methods have been developed for their synthesis, new approaches to polysubstituted …