Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Light-sheet fluorescence microscopy has transformed our ability to visualize and
quantitatively measure biological processes rapidly and over long time periods. In this …

Induced pluripotent stem cell (iPSC)-derived organoids provide models to study human
organ development. Single-cell transcriptomics enable highly resolved descriptions of cell …

We present Labkit, a user-friendly Fiji plugin for the segmentation of microscopy image data.
It offers easy to use manual and automated image segmentation routines that can be rapidly …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

Embryo development requires biochemical signalling to generate patterns of cell fates and
active mechanical forces to drive tissue shape changes. However, how these processes are …

From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …

Cell packing—the spatial arrangement of cells—determines the shapes of organs. Recently,
investigations of organ development in a variety of model organisms have uncovered …

The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …